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cfap43 cilia and flagella associated protein 43 [ Danio rerio (zebrafish) ]

Gene ID: 568701, updated on 4-Jan-2025

Summary

Official Symbol
cfap43provided by ZNC
Official Full Name
cilia and flagella associated protein 43provided by ZNC
Primary source
ZFIN:ZDB-GENE-080815-3
See related
Ensembl:ENSDARG00000001825 AllianceGenome:ZFIN:ZDB-GENE-080815-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wdr96; gb:ee329193; si:ch211-223p8.5
Summary
Predicted to be located in cytoplasm and motile cilium. Human ortholog(s) of this gene implicated in normal pressure hydrocephalus and spermatogenic failure 19. Orthologous to human CFAP43 (cilia and flagella associated protein 43). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See cfap43 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (24717880..24743151)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (24587436..24612701)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene sperm flagellar 1 Neighboring gene ER lipid raft associated 1 Neighboring gene collagen, type XVII, alpha 1b Neighboring gene SWI5-dependent homologous recombination repair protein 1 Neighboring gene STE20-like kinase a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
WD repeat-containing protein C10orf79; cilia- and flagella-associated protein 43
Names
WD repeat domain 96

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    24717880..24743151
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_692047.6XP_697139.4  cilia- and flagella-associated protein 43

    UniProtKB/TrEMBL
    A0A8N7TBN9
    Related
    ENSDARP00000123525.1, ENSDART00000147713.2
    Conserved Domains (4) summary
    pfam05483
    Location:10721610
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    COG2319
    Location:283544
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:343389
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:93443
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...