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ppp6r2b protein phosphatase 6, regulatory subunit 2b [ Danio rerio (zebrafish) ]

Gene ID: 570360, updated on 4-Jan-2025

Summary

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Official Symbol
ppp6r2bprovided by ZNC
Official Full Name
protein phosphatase 6, regulatory subunit 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070705-441
See related
Ensembl:ENSDARG00000069654 AllianceGenome:ZFIN:ZDB-GENE-070705-441
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ppp6r2; si:dkey-266m15.3
Summary
Predicted to enable protein phosphatase regulator activity. Predicted to be involved in regulation of signal transduction. Predicted to be active in cytosol and nucleus. Orthologous to human PPP6R2 (protein phosphatase 6 regulatory subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See ppp6r2b in Genome Data Viewer
Location:
chromosome: 18
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (6813977..6856015, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (6853057..6897215, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene adrenomedullin 2b Neighboring gene MOB kinase activator 2 Neighboring gene uncharacterized LOC101882393 Neighboring gene DnaJ heat shock protein family (Hsp40) member A2b Neighboring gene kielin cysteine rich BMP regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels. Zhang J, et al. FASEB J, 2023 May. PMID 37086087
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
  
enables protein phosphatase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine/threonine-protein phosphatase 6 regulatory subunit 2
Names
SAPS domain family, member 2
protein phosphatase 6, regulatory subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    6813977..6856015 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003200421.6 → XP_003200469.2  serine/threonine-protein phosphatase 6 regulatory subunit 2

    See identical proteins and their annotated locations for XP_003200469.2

    UniProtKB/TrEMBL
    A0A8M1RJ83, F1Q753
    Related
    ENSDARP00000143827.1, ENSDART00000175747.2
    Conserved Domains (1) summary
    pfam04499
    Location:128 → 528
    SAPS; SIT4 phosphatase-associated protein
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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