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dnai1.1 dynein, axonemal, intermediate chain 1, paralog 1 [ Danio rerio (zebrafish) ]

Gene ID: 570363, updated on 4-Jan-2025

Summary

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Official Symbol
dnai1.1provided by ZNC
Official Full Name
dynein, axonemal, intermediate chain 1, paralog 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040910-7
See related
Ensembl:ENSDARG00000100081 AllianceGenome:ZFIN:ZDB-GENE-040910-7
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dnai1; si:ch73-182i17.2
Summary
Acts upstream of or within determination of heart left/right asymmetry. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See dnai1.1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (18292535..18304018)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (18259177..18267366)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene bromodomain containing 3a Neighboring gene WD repeat domain 5 Neighboring gene uncharacterized LOC137488864 Neighboring gene RIMS binding protein 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia. Li Y, et al. PLoS Genet, 2016 Feb. PMID 26918822, Free PMC Article
  2. Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility. Zhao L, et al. Proc Natl Acad Sci U S A, 2013 Jul 30. PMID 23858445, Free PMC Article
  3. Comparative analysis of the testis and ovary transcriptomes in zebrafish by combining experimental and computational tools. Li Y, et al. Comp Funct Genomics, 2004. PMID 18629171, Free PMC Article
  4. Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing. Tang Q, et al. J Exp Med, 2017 Oct 2. PMID 28878000, Free PMC Article
  5. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Choksi SP, et al. Development, 2014 Sep. PMID 25139857, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within determination of heart left/right asymmetry IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
dynein axonemal intermediate chain 1
Names
dynein, axonemal, intermediate polypeptide 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    18292535..18304018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021469050.2 → XP_021324725.2  dynein axonemal intermediate chain 1

    Related
    ENSDARP00000134180.1, ENSDART00000170205.2
Nucleotide Protein Strain
Heading Accession and Version

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