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uckl1a uridine-cytidine kinase 1-like 1a [ Danio rerio (zebrafish) ]

Gene ID: 570547, updated on 4-Jan-2025

Summary

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Official Symbol
uckl1aprovided by ZNC
Official Full Name
uridine-cytidine kinase 1-like 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040724-238
See related
Ensembl:ENSDARG00000001686 AllianceGenome:ZFIN:ZDB-GENE-040724-238
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
uckl1; zK70P6.2; si:dkey-70p6.2
Summary
Predicted to enable ATP binding activity and uridine kinase activity. Predicted to be involved in CTP salvage and UMP salvage. Predicted to act upstream of or within phosphorylation. Orthologous to human UCKL1 (uridine-cytidine kinase 1 like 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See uckl1a in Genome Data Viewer
Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23009662..23028542)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (22988423..23008668)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene elastin microfibril interfacer 3a Neighboring gene sterile alpha motif domain containing 10a Neighboring gene si:dkey-70p6.1 Neighboring gene sodium/potassium transporting ATPase interacting 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables uridine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in CTP salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in UMP salvage IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uridine-cytidine kinase-like 1a
Names
uridine-cytidine kinase 1-like 1
uridine/cytidine kinase-like 1
NP_001121731.1
XP_005167107.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128259.1 → NP_001121731.1  uridine-cytidine kinase-like 1a

    Status: PROVISIONAL

    Source sequence(s)
    BX649575
    UniProtKB/TrEMBL
    A0A8M1NH97, B0S7A4
    Related
    ENSDARP00000038740.6, ENSDART00000030885.7
    Conserved Domains (3) summary
    COG0572
    Location:79 → 286
    Udk; Uridine kinase [Nucleotide transport and metabolism]
    cd02023
    Location:80 → 279
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
    pfam14681
    Location:309 → 512
    UPRTase; Uracil phosphoribosyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    23009662..23028542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167050.5 → XP_005167107.1  uridine-cytidine kinase-like 1a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BF24
    Conserved Domains (3) summary
    COG0572
    Location:93 → 300
    Udk; Uridine kinase [Nucleotide transport and metabolism]
    cd02023
    Location:94 → 293
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
    pfam14681
    Location:323 → 526
    UPRTase; Uracil phosphoribosyltransferase

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395272.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    257670..276480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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