U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

bud23 BUD23 rRNA methyltransferase and ribosome maturation factor [ Danio rerio (zebrafish) ]

Gene ID: 572367, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
bud23provided by ZNC
Official Full Name
BUD23 rRNA methyltransferase and ribosome maturation factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070410-68
See related
Ensembl:ENSDARG00000063596 AllianceGenome:ZFIN:ZDB-GENE-070410-68
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wbscr22; zgc:162306
Summary
Predicted to enable rRNA (guanine) methyltransferase activity. Predicted to be involved in rRNA (guanine-N7)-methylation. Predicted to act upstream of or within methylation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human BUD23 (BUD23 rRNA methyltransferase and ribosome maturation factor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See bud23 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (1749843..1765116, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (1784934..1800207, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene RAB guanine nucleotide exchange factor (GEF) 1, like Neighboring gene syntaxin 1A (brain) Neighboring gene cullin 3b Neighboring gene family with sequence similarity 124 member B Neighboring gene matrix metallopeptidase 28

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (guanine) methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (guanine) methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA (guanine-N7)-methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within rRNA (guanine-N7)-methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
18S rRNA (guanine-N(7))-methyltransferase
Names
Williams Beuren syndrome chromosome region 22
NP_001076348.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082879.1 → NP_001076348.1  18S rRNA (guanine-N(7))-methyltransferase

    See identical proteins and their annotated locations for NP_001076348.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133941
    UniProtKB/TrEMBL
    A0A8M1NBY6, A3KNP4
    Related
    ENSDARP00000087506.4, ENSDART00000093074.6
    Conserved Domains (2) summary
    pfam08241
    Location:58 → 133
    Methyltransf_11; Methyltransferase domain
    pfam12589
    Location:204 → 280
    WBS_methylT; Methyltransferase involved in Williams-Beuren syndrome

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    1749843..1765116 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools