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Mrps31 mitochondrial ribosomal protein S31 [ Mus musculus (house mouse) ]

Gene ID: 57312, updated on 27-Nov-2024

Summary

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Official Symbol
Mrps31provided by MGI
Official Full Name
mitochondrial ribosomal protein S31provided by MGI
Primary source
MGI:MGI:1913153
See related
Ensembl:ENSMUSG00000031533 AllianceGenome:MGI:1913153
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Imogen38; Imogen44; 1500002D03Rik
Summary
Predicted to enable protein domain specific binding activity. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; gonad; gut; and lung. Orthologous to human MRPS31 (mitochondrial ribosomal protein S31). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 11.7), liver E14 (RPKM 7.7) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Mrps31 in Genome Data Viewer
Location:
8 A2; 8 11.28 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22901356..22919685)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (22410449..22429669)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1810012K16 gene Neighboring gene STARR-positive B cell enhancer ABC_E6625 Neighboring gene predicted gene, 53406 Neighboring gene PDZ and LIM domain protein 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_20903 Neighboring gene STARR-seq mESC enhancer starr_20904 Neighboring gene predicted gene, 39140 Neighboring gene small integral membrane protein 19 Neighboring gene solute carrier family 20, member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient. Arden SD, et al. J Clin Invest, 1996 Jan 15. PMID 8567980, Free PMC Article
  2. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Doucet-Beaupré H, et al. Proc Natl Acad Sci U S A, 2016 Jul 26. PMID 27407143, Free PMC Article
  3. Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment. Osipovich AB, et al. Genome Res, 2005 Mar. PMID 15741512, Free PMC Article
  4. Ribosome. The structure of the human mitochondrial ribosome. Amunts A, et al. Science, 2015 Apr 3. PMID 25838379, Free PMC Article
  5. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
  
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein mS31
Names
28S ribosomal protein S31, mitochondrial
MRP-S31
S31mt
imogen 38
islet mitochondrial antigen, 38 kD

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020560.2 → NP_065585.1  small ribosomal subunit protein mS31 precursor

    See identical proteins and their annotated locations for NP_065585.1

    Status: VALIDATED

    Source sequence(s)
    AK005110, BY237441
    Consensus CDS
    CCDS22176.1
    UniProtKB/Swiss-Prot
    Q3TSP5, Q61733, Q8VEH4, Q9D045
    Related
    ENSMUSP00000033934.4, ENSMUST00000033934.5
    Conserved Domains (1) summary
    pfam15433
    Location:85 → 377
    MRP-S31; Mitochondrial 28S ribosomal protein S31

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    22901356..22919685
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312924.3 → XP_017168413.1  small ribosomal subunit protein mS31 isoform X1

    Conserved Domains (1) summary
    pfam15433
    Location:27 → 281
    MRP-S31; Mitochondrial 28S ribosomal protein S31

RNA

  1. XR_003947320.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q61733.1 GenPept UniProtKB/Swiss-Prot:Q61733

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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