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clos - closca

Involved in axis specification; torso signaling pathway; and vitelline membrane formation involved in chorion-containing eggshell formation. Located in extracellular region. Is expressed in oocyte and spermatozoon. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 98; ectodermal dysplasia 14; and tooth agenesis. Orthologous to human TSPEAR (thrombospondin type laminin G domain and EAR repeats). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa