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JYalpha JYalpha [ Drosophila melanogaster (fruit fly) ]

Gene ID: 5740846, updated on 9-Dec-2024

Summary

Official Symbol
JYalphaprovided by FlyBase
Official Full Name
JYalphaprovided by FlyBase
Primary source
FLYBASE:FBgn0267363
Locus tag
Dmel_CG45760
See related
AllianceGenome:FB:FBgn0267363
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17923; CG40625; CG45760; Dmel\CG45760; JY-alpha; Jyalpha; JYAlpha
Old locus tag
Dmel_CG17923; Dmel_CG40625
Summary
Predicted to enable P-type sodium:potassium-exchanging transporter activity. Involved in flagellated sperm motility. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See JYalpha in Genome Data Viewer
Location:
101F1-101F1; 4-0 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (879..5039)

Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

Genomic Sequence:
NC_004353.4 Chromosome 4 Reference Release 6 plus ISO1 MT Primary Assembly

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables P-type potassium transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables P-type sodium:potassium-exchanging transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables P-type sodium:potassium-exchanging transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in flagellated sperm motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in monoatomic cation transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sodium ion export across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
JYalpha
Names
CG45760-PB
JYalpha-PB
NP_001104092.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004353.4 Reference assembly

    Range
    879..5039
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001110622.3NP_001104092.2  JYalpha [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001104092.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8QI34, Q9U458
    Conserved Domains (6) summary
    smart00831
    Location:29102
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    COG4087
    Location:673738
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01106
    Location:171009
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    pfam00122
    Location:123354
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:785994
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam13246
    Location:416509
    Cation_ATPase; Cation transport ATPase (P-type)