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frd dihydrofolate reductase [ Escherichia phage JS98 ]

Gene ID: 5783726, updated on 7-Jan-2023

Summary

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Gene symbol
frd
Gene description
dihydrofolate reductase
Locus tag
EpJS98_gp227
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia phage JS98 (nat-host: Escherichia coli)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Straboviridae; Tevenvirinae; Dhakavirus
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Genomic context

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Sequence:
NC_010105.1 (144416..145000, complement)

NC_010105.1Genomic Context describing neighboring genes Neighboring gene NrdA-like aerobic NDP reductase large subunit Neighboring gene hypothetical protein Neighboring gene thymidylate synthase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene DUF5417 domain-containing protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_010105.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fumarate-Mediated Persistence of Escherichia coli against Antibiotics. Kim JS, et al. Antimicrob Agents Chemother, 2016 Apr. PMID 26810657, Free PMC Article
  2. Genome analysis of phage JS98 defines a fourth major subgroup of T4-like phages in Escherichia coli. Zuber S, et al. J Bacteriol, 2007 Nov. PMID 17693496, Free PMC Article
  3. Comparative genomics of the T4-Like Escherichia coli phage JS98: implications for the evolution of T4 phages. Chibani-Chennoufi S, et al. J Bacteriol, 2004 Dec. PMID 15576776, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
dihydrofolate reductase
YP_001595356.1
  • similar to bacteriophage T4 Frd dihydrofolate reductase; T4 frd-like, dihydrofolate reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_010105.1 Reference assembly

    Range
    144416..145000 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001595356.1 dihydrofolate reductase [Escherichia phage JS98]

    See identical proteins and their annotated locations for YP_001595356.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q5QC59
    Conserved Domains (1) summary
    cl17279
    Location:1 → 150
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...
Nucleotide Protein
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