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GstD10 Glutathione S transferase D10 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 59240, updated on 4-Jan-2025

Summary

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Official Symbol
GstD10provided by FlyBase
Official Full Name
Glutathione S transferase D10provided by FlyBase
Primary source
FLYBASE:FBgn0042206
Locus tag
Dmel_CG18548
See related
AllianceGenome:FB:FBgn0042206
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17392; CG18548; Dmel\CG18548; DmGSTD10; gstd10; GSTD10
Summary
Enables glutathione transferase activity. Involved in glutathione metabolic process. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See GstD10 in Genome Data Viewer
Location:
87B8-87B8; 3-52 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12364776..12365735, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8190498..8191457, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene small non-coding RNA 419 Neighboring gene Tim17a1 Neighboring gene Glutathione S transferase D9 Neighboring gene Glutathione S transferase D1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding. Wongsantichon J, et al. Arch Biochem Biophys, 2012 May. PMID 22475449
  2. Behavioral and Transcriptional Response to Selection for Olfactory Behavior in Drosophila. Brown EB, et al. G3 (Bethesda), 2020 Apr 9. PMID 32024668, Free PMC Article
  3. Mitogen-activated protein kinase p38b interaction with delta class glutathione transferases from the fruit fly, Drosophila melanogaster. Wongtrakul J, et al. J Insect Sci, 2012. PMID 23438069, Free PMC Article
  4. Cloning, expression and biochemical characterization of one Epsilon-class (GST-3) and ten Delta-class (GST-1) glutathione S-transferases from Drosophila melanogaster, and identification of additional nine members of the Epsilon class. Sawicki R, et al. Biochem J, 2003 Mar 1. PMID 12443531, Free PMC Article
  5. Structural and Thermodynamic Insights into Dimerization Interfaces of Drosophila Glutathione Transferases. Schwartz M, et al. Biomolecules, 2024 Jun 26. PMID 39062472, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutathione metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
glutathione S transferase D10
Names
CG18548-PA
CG18548-PB
GstD10-PA
GstD10-PB
NP_001287302.1
NP_652713.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12364776..12365735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144456.3 → NP_652713.1  glutathione S transferase D10, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652713.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGA1
    Related
    FBpp0082079
    Conserved Domains (2) summary
    cd03177
    Location:89 → 205
    GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
    cd03045
    Location:1 → 75
    GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...

  2. NM_001300373.1 → NP_001287302.1  glutathione S transferase D10, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287302.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGA1
    Conserved Domains (2) summary
    cd03177
    Location:89 → 205
    GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
    cd03045
    Location:1 → 75
    GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VGA1 Q9VGA1

Gene LinkOut

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