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BIN1 bridging integrator 1 [ Bos taurus (domestic cattle) ]

Gene ID: 614576, updated on 30-Jan-2025

Summary

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Official Symbol
BIN1provided by VGNC
Official Full Name
bridging integrator 1provided by VGNC
Primary source
VGNC:VGNC:26497
See related
BGD:BT25620; EnsemblRapid:ENSBTAG00070002558
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See BIN1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (5418320..5475073)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL6-like Neighboring gene histone H2A type 1-B Neighboring gene microRNA mir-2350 Neighboring gene uncharacterized LOC132342935 Neighboring gene serine protease 58

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC128846

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myc box-dependent-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046541.1 → NP_001040006.1  myc box-dependent-interacting protein 1

    See identical proteins and their annotated locations for NP_001040006.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105557
    UniProtKB/TrEMBL
    A0A3Q1MU19, Q2KJ23
    Conserved Domains (2) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:361 → 432
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    5418320..5475073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010801800.4 → XP_010800102.1  myc box-dependent-interacting protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LV21
    Conserved Domains (2) summary
    cd07611
    Location:31 → 272
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:530 → 601
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  2. XM_010801803.4 → XP_010800105.1  myc box-dependent-interacting protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1M808
    Related
    ENSBTAP00070003490.1, ENSBTAT00070006020.1
    Conserved Domains (2) summary
    cd07611
    Location:31 → 272
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:486 → 557
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  3. XM_010801805.4 → XP_010800107.1  myc box-dependent-interacting protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A3Q1M808
    Conserved Domains (2) summary
    cd12139
    Location:450 → 521
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:31 → 272
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  4. XM_010801806.4 → XP_010800108.1  myc box-dependent-interacting protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q1M808
    Conserved Domains (2) summary
    cd07611
    Location:31 → 272
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:443 → 514
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  5. XM_010801809.4 → XP_010800111.1  myc box-dependent-interacting protein 1 isoform X16

    UniProtKB/TrEMBL
    A0A3Q1MU19
    Conserved Domains (2) summary
    cd12139
    Location:407 → 478
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:31 → 272
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  6. XM_024977732.2 → XP_024833500.1  myc box-dependent-interacting protein 1 isoform X20

    UniProtKB/TrEMBL
    A0A3Q1M026
    Conserved Domains (2) summary
    cd12139
    Location:384 → 455
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:31 → 272
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  7. XM_005202217.5 → XP_005202274.1  myc box-dependent-interacting protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LV21, E1BNG8
    Related
    ENSBTAP00070003485.1, ENSBTAT00070006009.1
    Conserved Domains (3) summary
    cd07611
    Location:31 → 272
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:515 → 586
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl26386
    Location:372 → 513
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  8. XM_024977693.2 → XP_024833461.1  myc box-dependent-interacting protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A3Q1M808
    Conserved Domains (2) summary
    cd12139
    Location:435 → 506
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:31 → 272
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  9. XM_005202222.5 → XP_005202279.1  myc box-dependent-interacting protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A3Q1M808, A0A3Q1NHQ0
    Conserved Domains (3) summary
    cd07611
    Location:31 → 272
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:428 → 499
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl26386
    Location:281 → 426
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  10. XM_024977722.2 → XP_024833490.1  myc box-dependent-interacting protein 1 isoform X19

    UniProtKB/TrEMBL
    A0A3Q1MU19, A0A3Q1NGS3
    Conserved Domains (2) summary
    cd12139
    Location:392 → 463
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:31 → 272
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  11. XM_024977745.2 → XP_024833513.1  myc box-dependent-interacting protein 1 isoform X22

    UniProtKB/TrEMBL
    A0A3Q1M026
    Conserved Domains (2) summary
    cd12139
    Location:369 → 440
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:31 → 272
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  12. XM_010801801.3 → XP_010800103.1  myc box-dependent-interacting protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LV21
    Conserved Domains (2) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:499 → 570
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  13. XM_005202220.4 → XP_005202277.1  myc box-dependent-interacting protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A3Q1M808
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:455 → 526
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl25496
    Location:301 → 480
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  14. XM_005202223.4 → XP_005202280.1  myc box-dependent-interacting protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A3Q1M026, A0A3Q1N5F9
    Related
    ENSBTAP00070003452.1, ENSBTAT00070005940.1
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:419 → 490
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl25496
    Location:301 → 400
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  15. XM_005202224.4 → XP_005202281.1  myc box-dependent-interacting protein 1 isoform X15

    UniProtKB/TrEMBL
    A0A3Q1M026
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:412 → 483
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl26386
    Location:273 → 410
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  16. XM_005202227.3 → XP_005202284.1  myc box-dependent-interacting protein 1 isoform X21

    UniProtKB/TrEMBL
    A0A3Q1MU19
    Related
    ENSBTAP00070003509.1, ENSBTAT00070006054.1
    Conserved Domains (2) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:376 → 447
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  17. XM_015474474.2 → XP_015329960.1  myc box-dependent-interacting protein 1 isoform X23

    UniProtKB/TrEMBL
    A0A3Q1M026
    Related
    ENSBTAP00070003442.1, ENSBTAT00070005924.1
    Conserved Domains (2) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:353 → 424
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  18. XM_005202218.4 → XP_005202275.1  myc box-dependent-interacting protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LV21
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:484 → 555
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl26386
    Location:341 → 482
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  19. XM_005202221.4 → XP_005202278.1  myc box-dependent-interacting protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A3Q1M808, F6R9I4
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:440 → 511
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl25496
    Location:286 → 465
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  20. XM_005202225.4 → XP_005202282.1  myc box-dependent-interacting protein 1 isoform X17

    UniProtKB/TrEMBL
    A0A3Q1M026
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:404 → 475
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl25496
    Location:286 → 385
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  21. XM_005202226.5 → XP_005202283.1  myc box-dependent-interacting protein 1 isoform X18

    UniProtKB/TrEMBL
    A0A3Q1M026
    Related
    ENSBTAP00070003497.1, ENSBTAT00070006032.1
    Conserved Domains (3) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:397 → 468
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl26386
    Location:250 → 395
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  22. XM_005202228.3 → XP_005202285.1  myc box-dependent-interacting protein 1 isoform X24

    See identical proteins and their annotated locations for XP_005202285.1

    UniProtKB/TrEMBL
    A0A3Q1M026
    Conserved Domains (2) summary
    cd07611
    Location:31 → 241
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:338 → 409
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

  23. XM_010801804.3 → XP_010800106.1  myc box-dependent-interacting protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A3Q1LV21
    Conserved Domains (2) summary
    cd12139
    Location:456 → 527
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:1 → 198
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  24. XM_010801807.3 → XP_010800109.1  myc box-dependent-interacting protein 1 isoform X13

    UniProtKB/TrEMBL
    A0A3Q1ML09
    Conserved Domains (2) summary
    cd12139
    Location:425 → 496
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
    cl12013
    Location:1 → 167
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  25. XM_024977754.2 → XP_024833522.1  myc box-dependent-interacting protein 1 isoform X25

    UniProtKB/TrEMBL
    A0A3Q1ML09
    Conserved Domains (2) summary
    cd07611
    Location:7 → 217
    BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
    cd12139
    Location:314 → 385
    SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
Nucleotide Protein Strain
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