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Cdca7l cell division cycle associated 7 like [ Rattus norvegicus (Norway rat) ]

Gene ID: 619566, updated on 27-Nov-2024

Summary

Official Symbol
Cdca7lprovided by RGD
Official Full Name
cell division cycle associated 7 likeprovided by RGD
Primary source
RGD:1564080
See related
EnsemblRapid:ENSRNOG00000005410 AllianceGenome:RGD:1564080
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within positive regulation of cell population proliferation. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human CDCA7L (cell division cycle associated 7 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 139.3), Spleen (RPKM 55.3) and 8 other tissues See more
Orthologs
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Genomic context

See Cdca7l in Genome Data Viewer
Location:
6q33
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (144936885..144982844)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (138793953..138839889)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (145739570..145785607)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene Rap guanine nucleotide exchange factor 5 Neighboring gene uncharacterized LOC134479493 Neighboring gene 60S acidic ribosomal protein P2 pseudogene Neighboring gene small nucleolar RNA SNORA7 Neighboring gene ribosomal protein L32, pseudogene 3 Neighboring gene uncharacterized LOC120093173 Neighboring gene dynein, axonemal, heavy chain 11 Neighboring gene uncharacterized LOC134479494

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in fibrillar center IEA
Inferred from Electronic Annotation
more info
 
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell division cycle-associated 7-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034953.1NP_001030125.1  cell division cycle-associated 7-like protein

    See identical proteins and their annotated locations for NP_001030125.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098734
    UniProtKB/Swiss-Prot
    Q4G059
    UniProtKB/TrEMBL
    A0A0G2K8U6, A6KDM3
    Related
    ENSRNOP00000079873.2, ENSRNOT00000103690.2
    Conserved Domains (1) summary
    pfam10497
    Location:333431
    zf-4CXXC_R1; Zinc-finger domain of monoamine-oxidase A repressor R1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    144936885..144982844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594339.3XP_017449828.1  cell division cycle-associated 7-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I6G5U7