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Vmn2r35 vomeronasal 2, receptor 35 [ Mus musculus (house mouse) ]

Gene ID: 625353, updated on 27-Nov-2024

Summary

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Official Symbol
Vmn2r35provided by MGI
Official Full Name
vomeronasal 2, receptor 35provided by MGI
Primary source
MGI:MGI:3646200
See related
Ensembl:ENSMUSG00000096399 AllianceGenome:MGI:3646200
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG625353
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Vmn2r35 in Genome Data Viewer
Location:
7 A1; 7 4.52 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (7789150..7822866, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (7786151..7819867, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor, pseudogene 38 Neighboring gene STARR-seq mESC enhancer starr_18007 Neighboring gene vomeronasal 2, receptor, pseudogene 39 Neighboring gene vomeronasal 2, receptor, pseudogene 40 Neighboring gene vomeronasal 2, receptor 36

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development. Yamamoto H, et al. Cell Rep, 2020 Jan 21. PMID 31968244
  2. Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Yogosawa S, et al. Commun Biol, 2021 Oct 20. PMID 34671097, Free PMC Article
  3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal receptor Vmn2r35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105067.1 → NP_001098537.1  vomeronasal receptor Vmn2r35 precursor

    Status: INFERRED

    Source sequence(s)
    AC134573
    Consensus CDS
    CCDS51998.1
    UniProtKB/TrEMBL
    D3YZG0, D3Z0C4, D3Z2B6, E9PWC6, E9PWN9, E9Q076, E9Q1V1, E9Q228, E9Q2E3, E9Q3U0, E9Q7U8, F6V5C2, F7A495, K7N652
    Related
    ENSMUSP00000133007.2, ENSMUST00000169683.2
    Conserved Domains (4) summary
    pfam00003
    Location:599 → 833
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:75 → 453
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:513 → 564
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:39 → 503
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    7789150..7822866 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153315.1 → XP_036009208.1  vomeronasal receptor Vmn2r35 isoform X1

    UniProtKB/TrEMBL
    K7N652
    Conserved Domains (3) summary
    cd15283
    Location:551 → 786
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:43 → 503
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:512 → 557
    NCD3G; Nine Cysteines Domain of family 3 GPCR
Nucleotide Protein
Heading Accession and Version

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