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Fbxo39 F-box protein 39 [ Mus musculus (house mouse) ]

Gene ID: 628100, updated on 27-Nov-2024

Summary

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Official Symbol
Fbxo39provided by MGI
Official Full Name
F-box protein 39provided by MGI
Primary source
MGI:MGI:3505735
See related
Ensembl:ENSMUSG00000070388 AllianceGenome:MGI:3505735
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700010H23Rik
Summary
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO39 (F-box protein 39). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 42.6) See more
Orthologs
human all
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Genomic context

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See Fbxo39 in Genome Data Viewer
Location:
11 B4; 11 44.0 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (72205270..72210245)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (72314444..72319419)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 13 (sodium-dependent citrate transporter), member 5 Neighboring gene RIKEN cDNA 1700051A21 gene Neighboring gene STARR-seq mESC enhancer starr_29902 Neighboring gene XIAP associated factor 1 Neighboring gene predicted gene, 51867 Neighboring gene tektin 1 Neighboring gene predicted gene, 34317

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Systematic analysis and nomenclature of mammalian F-box proteins. Jin J, et al. Genes Dev, 2004 Nov 1. PMID 15520277, Free PMC Article
  2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
F-box only protein 39
Names
F-box protein 38

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099688.2 → NP_001093158.1  F-box only protein 39

    See identical proteins and their annotated locations for NP_001093158.1

    Status: PROVISIONAL

    Source sequence(s)
    AL929071, AV040000, BU937284, CR519476
    Consensus CDS
    CCDS36214.1
    UniProtKB/Swiss-Prot
    Q5NBU5
    Related
    ENSMUSP00000104144.2, ENSMUST00000108504.2
    Conserved Domains (1) summary
    pfam12937
    Location:16 → 57
    F-box-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    72205270..72210245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533901.3 → XP_006533964.2  F-box only protein 39 isoform X1

    Conserved Domains (1) summary
    pfam12937
    Location:53 → 94
    F-box-like

  2. XM_006533902.3 → XP_006533965.2  F-box only protein 39 isoform X2

    UniProtKB/Swiss-Prot
    Q5NBU5
    Conserved Domains (1) summary
    pfam12937
    Location:16 → 57
    F-box-like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5NBU5.2 GenPept UniProtKB/Swiss-Prot:Q5NBU5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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