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Zfp970 zinc finger protein 970 [ Mus musculus (house mouse) ]

Gene ID: 628308, updated on 4-Jan-2025

Summary

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Official Symbol
Zfp970provided by MGI
Official Full Name
zinc finger protein 970provided by MGI
Primary source
MGI:MGI:3652255
See related
Ensembl:ENSMUSG00000078866 AllianceGenome:MGI:3652255
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm14420
Summary
Predicted to enable DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and protein-macromolecule adaptor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including ZNF234 (zinc finger protein 234); ZNF254 (zinc finger protein 254); and ZNF28 (zinc finger protein 28). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Ubiquitous expression in bladder adult (RPKM 7.3), cerebellum adult (RPKM 4.3) and 25 other tissues See more
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Genomic context

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See Zfp970 in Genome Data Viewer
Location:
2 H4; 2 99.38 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (177156096..177170987)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (177464742..177479194)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118568489 Neighboring gene STARR-seq mESC enhancer starr_06678 Neighboring gene STARR-seq mESC enhancer starr_06679 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene STARR-seq mESC enhancer starr_06680 Neighboring gene predicted gene 14403 Neighboring gene STARR-seq mESC enhancer starr_06681 Neighboring gene STARR-seq mESC enhancer starr_06682 Neighboring gene novel KRAB box and zinc finger, C2H2 type domain containing protein Neighboring gene STARR-seq mESC enhancer starr_06683

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables damaged DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables protein-macromolecule adaptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
KRAB box and zinc finger C2H2 type domain containing protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177568.1 → NP_001171039.1  KRAB box and zinc finger C2H2 type domain containing protein-like

    See identical proteins and their annotated locations for NP_001171039.1

    Status: VALIDATED

    Source sequence(s)
    AL845468, BX294394
    Consensus CDS
    CCDS50831.1
    UniProtKB/TrEMBL
    F7CWF0, Q08BU3
    Related
    ENSMUSP00000104580.4, ENSMUST00000108952.4
    Conserved Domains (5) summary
    smart00349
    Location:4 → 45
    KRAB; krueppel associated box
    COG5048
    Location:75 → 477
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:441 → 461
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 43
    KRAB; KRAB box
    pfam13465
    Location:313 → 338
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    177156096..177170987
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162441.1 → XP_036018334.1  KRAB box and zinc finger C2H2 type domain containing protein-like isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:43 → 445
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:409 → 429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:450 → 474
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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