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Defb50 defensin beta 50 [ Rattus norvegicus (Norway rat) ]

Gene ID: 641639, updated on 9-Dec-2024

Summary

Official Symbol
Defb50provided by RGD
Official Full Name
defensin beta 50provided by RGD
Primary source
RGD:1563282
See related
EnsemblRapid:ENSRNOG00000033972 AllianceGenome:RGD:1563282
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in defense response to bacterium. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Defb50 in Genome Data Viewer
Location:
16q12.5
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (76956561..76969395, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (70254094..70266553, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (75249704..75262002, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene defensin beta 10 Neighboring gene defensin beta 2 Neighboring gene defensin beta 1 Neighboring gene defensin alpha 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
beta-defensin 50
Names
BD-50

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037513.2NP_001032602.1  beta-defensin 50 precursor

    See identical proteins and their annotated locations for NP_001032602.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/Swiss-Prot
    Q30KJ2
    Related
    ENSRNOP00000041922.3, ENSRNOT00000046156.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    76956561..76969395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063275689.1XP_063131759.1  beta-defensin 50 isoform X1

  2. XM_063275690.1XP_063131760.1  beta-defensin 50 isoform X2