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spoIVFB stage IV sporulation intramembrane metalloprotease SpoIVFB [ Bacillus toyonensis ]

Gene ID: 64185755, updated on 1-Dec-2024

Summary

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Gene symbol
spoIVFB
Gene description
stage IV sporulation intramembrane metalloprotease SpoIVFB
Locus tag
I0K03_RS21715
Gene type
protein coding
Organism
Bacillus toyonensis (strain: P18)
Lineage
Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group
Old locus tag
I0K03_21715
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Genomic context

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NZ_CP064875.1Genomic Context describing neighboring genes Neighboring gene Rne/Rng family ribonuclease Neighboring gene 50S ribosomal protein L21 Neighboring gene stage IV sporulation protein SpoIVFA Neighboring gene septum site-determining protein MinD Neighboring gene septum site-determining protein MinC

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP064875.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interaction of intramembrane metalloprotease SpoIVFB with substrate Pro-σ(K). Halder S, et al. Proc Natl Acad Sci U S A, 2017 Dec 12. PMID 29180425, Free PMC Article
  2. Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate, Pro-σK. Zhang Y, et al. J Biol Chem, 2016 May 6. PMID 26953342, Free PMC Article
  3. Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP. Zhou R, et al. Proc Natl Acad Sci U S A, 2009 Sep 22. PMID 19805276, Free PMC Article
  4. A branched pathway governing the activation of a developmental transcription factor by regulated intramembrane proteolysis. Campo N, et al. Mol Cell, 2006 Jul 7. PMID 16818230
  5. Evidence that SpoIVFB is a novel type of membrane metalloprotease governing intercompartmental communication during Bacillus subtilis sporulation. Yu YT, et al. J Bacteriol, 2000 Jun. PMID 10809718, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
stage IV sporulation intramembrane metalloprotease SpoIVFB
WP_000598976.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP064875.1 Reference assembly

    Range
    4288684..4289544 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_000598976.1 MULTISPECIES: stage IV sporulation intramembrane metalloprotease SpoIVFB [Bacillus]

    See identical proteins and their annotated locations for WP_000598976.1

    UniProtKB/TrEMBL
    A0A1D3PN63, A0A1V6LMF2, A0A8I1KLF4, A0AAJ1P0K0
    Conserved Domains (1) summary
    cd06161
    Location:10 → 204
    S2P-M50_SpoIVFB; SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F ...
Nucleotide Protein
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