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Mrpl23 mitochondrial ribosomal protein L23 [ Rattus norvegicus (Norway rat) ]

Gene ID: 64360, updated on 4-Jan-2025

Summary

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Official Symbol
Mrpl23provided by RGD
Official Full Name
mitochondrial ribosomal protein L23provided by RGD
Primary source
RGD:68343
See related
EnsemblRapid:ENSRNOG00000020354 AllianceGenome:RGD:68343
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rpl23l; rL23MRP; Rpl23-rs
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in fibrillar center and mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL23 (mitochondrial ribosomal protein L23). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Muscle (RPKM 346.2), Heart (RPKM 334.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mrpl23 in Genome Data Viewer
Location:
1q41
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (207116930..207124702)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (197687452..197695222)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (215701544..215709313)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene lymphocyte-specific protein 1 Neighboring gene proline rich 33 Neighboring gene troponin T3, fast skeletal type Neighboring gene uncharacterized LOC102548505 Neighboring gene microRNA 675 Neighboring gene H19 imprinted maternally expressed transcript Neighboring gene microRNA 483 Neighboring gene insulin-like growth factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
  2. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosolic ribosome IEA
Inferred from Electronic Annotation
more info
  
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL23m
Names
39S ribosomal protein L23, mitochondrial
L23 mitochondrial-related protein
L23mt
MRP-L23
ribosomal protein L23-related product homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022529.1 → NP_071974.1  large ribosomal subunit protein uL23m

    See identical proteins and their annotated locations for NP_071974.1

    Status: PROVISIONAL

    Source sequence(s)
    U62635
    UniProtKB/Swiss-Prot
    Q63750
    UniProtKB/TrEMBL
    A0A8L2QF35, A6HY67
    Related
    ENSRNOP00000081413.2, ENSRNOT00000104233.2
    Conserved Domains (1) summary
    pfam00276
    Location:42 → 105
    Ribosomal_L23; Ribosomal protein L23

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    207116930..207124702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063272761.1 → XP_063128831.1  large ribosomal subunit protein uL23m isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0K1, A0A8L2QF35
    Related
    ENSRNOP00000085090.1, ENSRNOT00000097083.2

  2. XM_063272765.1 → XP_063128835.1  large ribosomal subunit protein uL23m isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZRL1, A0A8L2QF35
    Related
    ENSRNOP00000104521.1, ENSRNOT00000136177.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q63750.1 GenPept UniProtKB/Swiss-Prot:Q63750

Gene LinkOut

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