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cpx - complexin

Predicted to enable SNARE binding activity. Involved in chemical synaptic transmission; negative regulation of neurotransmitter secretion; and synaptic assembly at neuromuscular junction. Located in several cellular components, including neuromuscular junction; presynaptic active zone; and type I terminal bouton. Is expressed in several structures, including adult head; larval central nervous system; neuromuscular junction; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 63. Orthologous to human CPLX1 (complexin 1) and CPLX2 (complexin 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa