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mutL DNA mismatch repair endonuclease MutL [ Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum) ]

Gene ID: 66261836, updated on 4-Dec-2024

Summary

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Gene symbol
mutL
Gene description
DNA mismatch repair endonuclease MutL
Locus tag
HDEF_RS10540
Gene type
protein coding
Organism
Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum) (strain: T5A, nat-host: Acyrthosiphon pisum)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; aphid secondary symbionts; Candidatus Hamiltonella
Old locus tag
HDEF_p0005
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Genomic context

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Location:
plasmid: pHD5AT
Sequence:
NC_012752.1 (3239..5011, complement)

NC_012752.1Genomic Context describing neighboring genes Neighboring gene LuxR C-terminal-related transcriptional regulator Neighboring gene PAS domain-containing protein Neighboring gene hypothetical protein Neighboring gene JmjC domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_012752.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MutL traps MutS at a DNA mismatch. Qiu R, et al. Proc Natl Acad Sci U S A, 2015 Sep 1. PMID 26283381, Free PMC Article
  2. Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors. Degnan PH, et al. Proc Natl Acad Sci U S A, 2009 Jun 2. PMID 19451630, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
DNA mismatch repair endonuclease MutL

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012752.1 Reference assembly

    Range
    3239..5011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_012738242.1 DNA mismatch repair endonuclease MutL [Candidatus Hamiltonella defensa]

    See identical proteins and their annotated locations for WP_012738242.1

    UniProtKB/TrEMBL
    C3M8B2
    Conserved Domains (4) summary
    PRK00095
    Location:1 → 565
    mutL; DNA mismatch repair protein; Reviewed
    cd03482
    Location:208 → 328
    MutL_Trans_MutL; MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL. EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second ...
    cl00075
    Location:23 → 149
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins
    cl07336
    Location:415 → 538
    MutL_C; MutL C terminal dimerization domain
Nucleotide Protein
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