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rstA toxin production/motility transcriptional repressor RstA [ Clostridioides difficile ]

Gene ID: 66356140, updated on 15-Dec-2024

Summary

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Gene symbol
rstA
Gene description
toxin production/motility transcriptional repressor RstA
Locus tag
KNZ77_RS18510
Gene type
protein coding
Organism
Clostridioides difficile (strain: S-0253, nat-host: Homo sapiens)
Lineage
Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Old locus tag
KNZ77_18510
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Genomic context

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NZ_CP076401.1Genomic Context describing neighboring genes Neighboring gene DUF3343 domain-containing protein Neighboring gene sulfurtransferase-like selenium metabolism protein YedF Neighboring gene GerMN domain-containing protein Neighboring gene aminotransferase class V-fold PLP-dependent enzyme

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP076401.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RstA Is a Major Regulator of Clostridioides difficile Toxin Production and Motility. Edwards AN, et al. mBio, 2019 Mar 12. PMID 30862746, Free PMC Article
  2. A novel regulator controls Clostridium difficile sporulation, motility and toxin production. Edwards AN, et al. Mol Microbiol, 2016 Jun. PMID 26915493, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
toxin production/motility transcriptional repressor RstA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP076401.1 Reference assembly

    Range
    4075947..4077239 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_009894114.1 toxin production/motility transcriptional repressor RstA [Clostridioides difficile]

    See identical proteins and their annotated locations for WP_009894114.1

    UniProtKB/TrEMBL
    A0A0H3NCE2, A0A9P3TYT1, A0A9R0CGA1, Q181S0
    Conserved Domains (4) summary
    cd00093
    Location:7 → 63
    HTH_XRE; Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.
    TIGR02917
    Location:78 → 419
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:156 → 183
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:238 → 308
    TPR_12; Tetratricopeptide repeat
Nucleotide Protein
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