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Mrpl20 mitochondrial ribosomal protein L20 [ Mus musculus (house mouse) ]

Gene ID: 66448, updated on 27-Nov-2024

Summary

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Official Symbol
Mrpl20provided by MGI
Official Full Name
mitochondrial ribosomal protein L20provided by MGI
Primary source
MGI:MGI:2137221
See related
Ensembl:ENSMUSG00000029066 AllianceGenome:MGI:2137221
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610008D01Rik; 4930425I20Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including extraembryonic component; ganglia; genitourinary system; jaw; and musculoskeletal system. Orthologous to human MRPL20 (mitochondrial ribosomal protein L20). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in liver E14 (RPKM 29.5), testis adult (RPKM 27.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Mrpl20 in Genome Data Viewer
Location:
4 E2; 4 87.44 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155887335..155893288)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155802878..155808831)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 88B Neighboring gene STARR-seq mESC enhancer starr_12274 Neighboring gene ankyrin repeat domain 65 Neighboring gene STARR-positive B cell enhancer ABC_E3560 Neighboring gene cyclin L2 Neighboring gene STARR-seq mESC enhancer starr_12275 Neighboring gene STARR-positive B cell enhancer ABC_E4740 Neighboring gene aurora kinase A interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin. Berke JD, et al. Neuron, 2001 Oct 25. PMID 11683997
  2. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
  3. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  4. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  5. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in mitochondrial ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial ribosome ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein bL20m
Names
39S ribosomal protein L20, mitochondrial
L20mt
MRP-L20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025570.3 → NP_079846.1  large ribosomal subunit protein bL20m precursor

    See identical proteins and their annotated locations for NP_079846.1

    Status: VALIDATED

    Source sequence(s)
    AK011341, AL670236, BC039985, CJ082585
    Consensus CDS
    CCDS19041.1
    UniProtKB/Swiss-Prot
    Q9CQL4, Q9D5L3
    Conserved Domains (1) summary
    pfam00453
    Location:15 → 113
    Ribosomal_L20; Ribosomal protein L20

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    155887335..155893288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164313.1 → XP_036020206.1  large ribosomal subunit protein bL20m isoform X1

    UniProtKB/Swiss-Prot
    Q9CQL4, Q9D5L3
    Related
    ENSMUSP00000030942.6, ENSMUST00000030942.13
    Conserved Domains (1) summary
    pfam00453
    Location:15 → 113
    Ribosomal_L20; Ribosomal protein L20
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQL4.1 GenPept UniProtKB/Swiss-Prot:Q9CQL4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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