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E6A31_RS00945 type II toxin-antitoxin system PemK/MazF family toxin [ Enterococcus faecium ]

Gene ID: 66453197, updated on 3-Dec-2024

Summary

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Gene symbol
E6A31_RS00945
Gene description
type II toxin-antitoxin system PemK/MazF family toxin
Locus tag
E6A31_RS00945
Gene type
protein coding
Organism
Enterococcus faecium (strain: SRR24, nat-host: Homo sapiens)
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Old locus tag
E6A31_00990
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Genomic context

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NZ_CP038996.1Genomic Context describing neighboring genes Neighboring gene holo-ACP synthase Neighboring gene alanine racemase Neighboring gene 30S ribosomal protein S14 Neighboring gene NADP-dependent oxidoreductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP038996.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tandem amplification of the vanM gene cluster drives vancomycin resistance in vancomycin-variable enterococci. Sun L, et al. J Antimicrob Chemother, 2020 Feb 1. PMID 31742612
  2. Structural basis of mRNA recognition and cleavage by toxin MazF and its regulation by antitoxin MazE in Bacillus subtilis. Simanshu DK, et al. Mol Cell, 2013 Nov 7. PMID 24120662, Free PMC Article
  3. Ribonucleases in bacterial toxin-antitoxin systems. Cook GM, et al. Biochim Biophys Acta, 2013 Jun-Jul. PMID 23454553
  4. Toxin-antitoxin systems: reversible toxicity. Hall AM, et al. Curr Opin Microbiol, 2017 Apr. PMID 28279904

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
type II toxin-antitoxin system PemK/MazF family toxin
WP_002289874.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP038996.1 Reference assembly

    Range
    193645..194007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_002289874.1 MULTISPECIES: type II toxin-antitoxin system PemK/MazF family toxin [Enterococcus]

    See identical proteins and their annotated locations for WP_002289874.1

    UniProtKB/TrEMBL
    A0A132P546, A0A1E9W5Q2, A0A242DKC9, A0A4Y3JLH8, A0A6N8GTF8, A0A828ZQS4, A0A829A8J0, A0A829FDB0, A0A829FMA2, A0A9P2S2F4, A0AAV3DVN1, A0AAV3DZP9, A0AAV3GYT5, A0AAV3L4J2, A0AAW9N3P9, J7CU41, J8WMR2, Q3XWD3, R2MHC2
    Conserved Domains (1) summary
    pfam02452
    Location:3 → 109
    PemK_toxin; PemK-like, MazF-like toxin of type II toxin-antitoxin system
Nucleotide Protein
Heading Accession and Version