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tnpB IS200/IS605 family element RNA-guided endonuclease TnpB [ Enterococcus faecium ]

Gene ID: 66454387, updated on 3-Dec-2024

Summary

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Gene symbol
tnpB
Gene description
IS200/IS605 family element RNA-guided endonuclease TnpB
Locus tag
E6A31_RS06900
Gene type
protein coding
Organism
Enterococcus faecium (strain: SRR24, nat-host: Homo sapiens)
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Old locus tag
E6A31_07345
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Genomic context

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NZ_CP038996.1Genomic Context describing neighboring genes Neighboring gene DUF2273 domain-containing protein Neighboring gene alkaline shock response membrane anchor protein AmaP Neighboring gene IS200/IS605-like element ISEfa4 family transposase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP038996.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the IS200/IS605 Insertion Sequence Family in Halanaerobium Hydrogeniformans. Sadler M, et al. Genes (Basel), 2020 Apr 29. PMID 32365520, Free PMC Article
  2. ISDra2 transposition in Deinococcus radiodurans is downregulated by TnpB. Pasternak C, et al. Mol Microbiol, 2013 Apr. PMID 23461641
  3. Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease. Karvelis T, et al. Nature, 2021 Nov. PMID 34619744, Free PMC Article
  4. Genetic features of the poxtA linezolid resistance gene in human enterococci from France. Dejoies L, et al. J Antimicrob Chemother, 2021 Jul 15. PMID 33895846
  5. Exploring bacterial insertion sequences with ISfinder: objectives, uses, and future developments. Siguier P, et al. Methods Mol Biol, 2012. PMID 22367867

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
IS200/IS605 family element RNA-guided endonuclease TnpB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP038996.1 Reference assembly

    Range
    1416861..1418009 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_002287525.1 MULTISPECIES: IS200/IS605 family element RNA-guided endonuclease TnpB [Bacteria]

    See identical proteins and their annotated locations for WP_002287525.1

    UniProtKB/TrEMBL
    A0A376H002, A0AAV3GV80, Q3Y110, Q8GF05
    Conserved Domains (1) summary
    COG0675
    Location:4 → 382
    InsQ; Transposase [Mobilome: prophages, transposons]
Nucleotide Protein
Heading Accession and Version