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E6A31_RS14175 type II toxin-antitoxin system RelE/ParE family toxin [ Enterococcus faecium ]

Gene ID: 66455833, updated on 30-Mar-2024

Summary

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Gene symbol
E6A31_RS14175
Gene description
type II toxin-antitoxin system RelE/ParE family toxin
Locus tag
E6A31_RS14175
Gene type
protein coding
Organism
Enterococcus faecium (strain: SRR24, nat-host: Homo sapiens)
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Old locus tag
E6A31_15030
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Genomic context

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Location:
plasmid: pSRR24

NZ_CP038997.1Genomic Context describing neighboring genes Neighboring gene IS6-like element IS1216 family transposase Neighboring gene hypothetical protein Neighboring gene DUF6290 family protein Neighboring gene AAA family ATPase

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP038997.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Emergence of vancomycin-resistant Enterococcus faecium ST1421 lacking the pstS gene in Korea. Kim HM, et al. Eur J Clin Microbiol Infect Dis, 2020 Jul. PMID 32128641
  2. Evolving new protein-protein interaction specificity through promiscuous intermediates. Aakre CD, et al. Cell, 2015 Oct 22. PMID 26478181, Free PMC Article
  3. Interaction specificity, toxicity and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems. Fiebig A, et al. Mol Microbiol, 2010 Jul 1. PMID 20487277, Free PMC Article
  4. A conserved mode of protein recognition and binding in a ParD-ParE toxin-antitoxin complex. Dalton KM, et al. Biochemistry, 2010 Mar 16. PMID 20143871, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
type II toxin-antitoxin system RelE/ParE family toxin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP038997.1 Reference assembly

    Range
    103595..103861 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010729835.1 MULTISPECIES: type II toxin-antitoxin system RelE/ParE family toxin [Enterococcus]

    See identical proteins and their annotated locations for WP_010729835.1

    UniProtKB/TrEMBL
    A0A1A7STW7, A0A829F177
    Conserved Domains (1) summary
    COG2026
    Location:1 → 88
    RelE; mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system [Defense mechanisms]
Nucleotide Protein
Heading Accession and Version