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Vmn2r54 vomeronasal 2, receptor 54 [ Mus musculus (house mouse) ]

Gene ID: 666085, updated on 27-Nov-2024

Summary

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Official Symbol
Vmn2r54provided by MGI
Official Full Name
vomeronasal 2, receptor 54provided by MGI
Primary source
MGI:MGI:3704110
See related
Ensembl:ENSMUSG00000096593 AllianceGenome:MGI:3704110
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm470; Gm1496; EG666085
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Vmn2r54 in Genome Data Viewer
Location:
7 A1; 7 7.57 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (12349160..12374167, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (12615233..12636134, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2900092C05 gene Neighboring gene STARR-seq mESC enhancer starr_18052 Neighboring gene ribosomal protein L5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18053 Neighboring gene vomeronasal 2, receptor 53 Neighboring gene PC4 and SFRS1 interacting protein 1 pseudogene Neighboring gene vomeronasal 2, receptor 55 Neighboring gene STARR-seq mESC enhancer starr_18054 Neighboring gene vomeronasal 2, receptor 56

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal 2, receptor 54
Names
V2R receptor
vomeronasal receptor Vmn2r54

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384946.1 → NP_001371875.1  vomeronasal 2, receptor 54 precursor

    Status: VALIDATED

    Source sequence(s)
    AC139131
    Consensus CDS
    CCDS52019.1
    UniProtKB/TrEMBL
    A0A8V5KYP3, K7N649
    Related
    ENSMUSP00000159503.1, ENSMUST00000240710.1
    Conserved Domains (4) summary
    cd06365
    Location:41 → 493
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:505 → 558
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd14964
    Location:615 → 636
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:601 → 829
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    12349160..12374167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153360.1 → XP_036009253.1  vomeronasal 2, receptor 54 isoform X1

    UniProtKB/TrEMBL
    A0A3B2W422, K7N649
    Related
    ENSMUSP00000156708.2, ENSMUST00000233287.2
    Conserved Domains (4) summary
    cd06365
    Location:41 → 493
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:514 → 567
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd14964
    Location:624 → 645
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:610 → 838
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081449.2: Suppressed sequence

    Description
    NM_001081449.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

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