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Spryd7 SPRY domain containing 7 [ Mus musculus (house mouse) ]

Gene ID: 66674, updated on 27-Nov-2024

Summary

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Official Symbol
Spryd7provided by MGI
Official Full Name
SPRY domain containing 7provided by MGI
Primary source
MGI:MGI:1913924
See related
Ensembl:ENSMUSG00000021930 AllianceGenome:MGI:1913924
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clld6; 6330409N04Rik
Summary
Orthologous to human SPRYD7 (SPRY domain containing 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E18 (RPKM 6.4), cerebellum adult (RPKM 6.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Spryd7 in Genome Data Viewer
Location:
14 D1; 14 33.05 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (61769300..61794335, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (61531851..61556886, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41169 Neighboring gene RIKEN cDNA 4930556J02 gene Neighboring gene vomeronasal 1 receptor, pseudogene 136 Neighboring gene nuclear encoded tRNA lysine 32 (anticodon CTT) Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:62175814-62175923 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_36882 Neighboring gene STARR-seq mESC enhancer starr_36883 Neighboring gene tripartite motif-containing 13 Neighboring gene deleted in lymphocytic leukemia, 2 Neighboring gene potassium channel regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
SPRY domain-containing protein 7
Names
CLL deletion region gene 6 protein homolog
chronic lymphocytic leukemia deletion region gene 6 protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310603.1 → NP_001297532.1  SPRY domain-containing protein 7 isoform 2

    See identical proteins and their annotated locations for NP_001297532.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK018153, AK137685, AK150789, CT009550
    Consensus CDS
    CCDS79330.1
    UniProtKB/TrEMBL
    Q3UBW1
    Related
    ENSMUSP00000098065.5, ENSMUST00000100496.5
    Conserved Domains (1) summary
    cl02614
    Location:35 → 130
    SPRY; SPRY domain

  2. NM_025697.4 → NP_079973.1  SPRY domain-containing protein 7 isoform 1

    See identical proteins and their annotated locations for NP_079973.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK018153, AK137685, CT009550
    Consensus CDS
    CCDS27185.1
    UniProtKB/Swiss-Prot
    Q3TFQ1, Q8K1Y1, Q9CU44, Q9D368, Q9D3D1
    Related
    ENSMUSP00000022497.9, ENSMUST00000022497.15
    Conserved Domains (1) summary
    cd12880
    Location:35 → 196
    SPRYD7; SPRY domain-containing protein 7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    61769300..61794335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245148.3 → XP_011243450.1  SPRY domain-containing protein 7 isoform X1

    Conserved Domains (1) summary
    cd12880
    Location:4 → 164
    SPRYD7; SPRY domain-containing protein 7
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TFQ1.2 GenPept UniProtKB/Swiss-Prot:Q3TFQ1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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