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Ppp1r14bl protein phosphatase 1, regulatory inhibitor subunit 14B like [ Mus musculus (house mouse) ]

Gene ID: 66755, updated on 27-Nov-2024

Summary

Official Symbol
Ppp1r14blprovided by MGI
Official Full Name
protein phosphatase 1, regulatory inhibitor subunit 14B likeprovided by MGI
Primary source
MGI:MGI:1914005
See related
Ensembl:ENSMUSG00000073730 AllianceGenome:MGI:1914005
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933415F23Rik
Summary
Predicted to enable protein serine/threonine phosphatase inhibitor activity. Acts upstream of or within innate immune response. Orthologous to human PPP1R14B (protein phosphatase 1 regulatory inhibitor subunit 14B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Ppp1r14bl in Genome Data Viewer
Location:
1 A5; 1 9.35 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (23139554..23141334, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (23100473..23102253, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_00424 Neighboring gene predicted gene 7759 Neighboring gene STARR-seq mESC enhancer starr_00425 Neighboring gene predicted gene 7761 Neighboring gene STARR-seq mESC enhancer starr_00426 Neighboring gene STARR-seq mESC enhancer starr_00427 Neighboring gene STARR-seq mESC enhancer starr_00428 Neighboring gene 4.5s RNA, pseudogene 4 Neighboring gene predicted gene, 30442

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within innate immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
protein phosphatase 1, regulatory (inhibitor) subunit 14B-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025746.2NP_080022.2  protein phosphatase 1, regulatory (inhibitor) subunit 14B-like

    See identical proteins and their annotated locations for NP_080022.2

    Status: VALIDATED

    Source sequence(s)
    AK016819, AV040646, BC115556
    Consensus CDS
    CCDS48231.1
    UniProtKB/TrEMBL
    Q14BX6
    Related
    ENSMUSP00000072920.6, ENSMUST00000073179.6
    Conserved Domains (1) summary
    pfam05361
    Location:23146
    PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    23139554..23141334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)