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Igkv4-59 immunoglobulin kappa variable 4-59 [ Mus musculus (house mouse) ]

Gene ID: 667683, updated on 2-Nov-2024

Summary

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Official Symbol
Igkv4-59provided by MGI
Official Full Name
immunoglobulin kappa variable 4-59provided by MGI
Primary source
MGI:MGI:3646808
See related
Ensembl:ENSMUSG00000094006 IMGT/GENE-DB:IGKV4-59; AllianceGenome:MGI:3646808
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
kk4; Gm8760; EG667683
Summary
Predicted to be involved in immune response. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Igkv4-59 in Genome Data Viewer
Location:
6 C1; 6 31.5 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (69415202..69415725, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (69438218..69438741, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene immunoglobulin kappa chain variable 13-61-1 Neighboring gene STARR-seq mESC enhancer starr_16214 Neighboring gene immunoglobulin kappa chain variable 4-61 Neighboring gene immunoglobulin kappa variable 4-60 Neighboring gene immunoglobulin kappa variable 4-58

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional analogues of the VKOx1 gene in different strains of mice: evolutionary conservation but diversity based on V-J joining. Kaartinen M, et al. J Immunol, 1987 Mar 1. PMID 3100644
  2. Sequences of variable regions of hybridoma antibodies to alpha (1----6) dextran in BALB/c and C57BL/6 mice. Sikder SK, et al. J Immunol, 1985 Dec. PMID 2415605
  3. Different VL and VH germ-line genes are used to produce similar combining sites with specificity for alpha(1----6)dextrans. Akolkar PN, et al. J Immunol, 1987 Jun 15. PMID 2438345
  4. Combinatorial association of V genes: one VH gene codes for three non-cross-reactive monoclonal antibodies each specific for a different antigen (phoxazolone, NP or gat). Kaartinen M, et al. Mol Immunol, 1988 Sep. PMID 3211160
  5. Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome. Schäble KF, et al. Eur J Immunol, 1999 Jul. PMID 10427970

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Other Names

  • immunoglobulin kappa chain variable 4-59
  • monoclonal antibody kappa light chain

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of immunoglobulin complex IBA
Inferred from Biological aspect of Ancestor
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005612.1 

    Range
    1883238..1883761 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    69415202..69415725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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Research Materials