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Ccdc127 coiled-coil domain containing 127 [ Mus musculus (house mouse) ]

Gene ID: 67433, updated on 27-Nov-2024

Summary

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Official Symbol
Ccdc127provided by MGI
Official Full Name
coiled-coil domain containing 127provided by MGI
Primary source
MGI:MGI:1914683
See related
Ensembl:ENSMUSG00000021578 AllianceGenome:MGI:1914683
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A430066A18; C130002N06; 0610011N22Rik; 5430420E17Rik
Summary
Orthologous to human CCDC127 (coiled-coil domain containing 127). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in heart adult (RPKM 14.1), cerebellum adult (RPKM 4.7) and 22 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc127 in Genome Data Viewer
Location:
13 C1; 13 40.17 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74498436..74513902)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (74350317..74365783)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene programmed cell death 6 Neighboring gene succinate dehydrogenase complex, subunit A, flavoprotein (Fp) Neighboring gene STARR-positive B cell enhancer ABC_E10800 Neighboring gene leucine rich repeat containing 14B Neighboring gene zinc finger protein 72 Neighboring gene STARR-seq mESC enhancer starr_35006 Neighboring gene BCL2-like 13 (apoptosis facilitator) pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7251 Neighboring gene STARR-seq mESC enhancer starr_35008 Neighboring gene ferritin light polypeptide 1, pseudogene 1 Neighboring gene microRNA 692-3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 127

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168658.1 → NP_001162129.1  coiled-coil domain-containing protein 127 isoform 2

    See identical proteins and their annotated locations for NP_001162129.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding region, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AK164539, CT009486
    Consensus CDS
    CCDS49314.1
    UniProtKB/TrEMBL
    E0CYP1
    Related
    ENSMUSP00000124193.2, ENSMUST00000160021.8

  2. NM_001168659.1 → NP_001162130.1  coiled-coil domain-containing protein 127 isoform 1

    See identical proteins and their annotated locations for NP_001162130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AK002564, AK164539, CT009486
    Consensus CDS
    CCDS26644.1
    UniProtKB/Swiss-Prot
    Q3TC33, Q3TPA8, Q9CQ15
    UniProtKB/TrEMBL
    E0CYX9
    Related
    ENSMUSP00000022063.8, ENSMUST00000022063.14
    Conserved Domains (1) summary
    pfam17380
    Location:47 → 137
    DUF5401; Family of unknown function (DUF5401)

  3. NM_024201.3 → NP_077163.1  coiled-coil domain-containing protein 127 isoform 1

    See identical proteins and their annotated locations for NP_077163.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AK164539, BC049099, CT009486
    Consensus CDS
    CCDS26644.1
    UniProtKB/Swiss-Prot
    Q3TC33, Q3TPA8, Q9CQ15
    UniProtKB/TrEMBL
    E0CYX9
    Related
    ENSMUSP00000123805.2, ENSMUST00000162376.2
    Conserved Domains (1) summary
    pfam17380
    Location:47 → 137
    DUF5401; Family of unknown function (DUF5401)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    74498436..74513902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TC33.2 GenPept UniProtKB/Swiss-Prot:Q3TC33

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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