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Tmed9 transmembrane p24 trafficking protein 9 [ Mus musculus (house mouse) ]

Gene ID: 67511, updated on 27-Nov-2024

Summary

Official Symbol
Tmed9provided by MGI
Official Full Name
transmembrane p24 trafficking protein 9provided by MGI
Primary source
MGI:MGI:1914761
See related
Ensembl:ENSMUSG00000058569 AllianceGenome:MGI:1914761
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2400003B06Rik
Summary
Predicted to enable syntaxin binding activity. Predicted to be involved in several processes, including Golgi organization; Golgi vesicle transport; and intracellular protein transport. Located in synaptic vesicle. Is expressed in embryo. Orthologous to human TMED9 (transmembrane p24 trafficking protein 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 76.5), limb E14.5 (RPKM 60.5) and 28 other tissues See more
Orthologs
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Genomic context

See Tmed9 in Genome Data Viewer
Location:
13 B1; 13 30.06 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55740948..55745510)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55593135..55597697)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46416 Neighboring gene family with sequence similarity 193, member B Neighboring gene predicted gene, 31364 Neighboring gene beta-1,4-galactosyltransferase 7 Neighboring gene calcium modulating ligand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables syntaxin binding IEA
Inferred from Electronic Annotation
more info
 
enables syntaxin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in COPI coating of Golgi vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in COPI coating of Golgi vesicle ISO
Inferred from Sequence Orthology
more info
 
involved_in COPI coating of Golgi vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
 
involved_in Golgi organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of organelle organization ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of organelle organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transmembrane emp24 domain-containing protein 9
Names
glycoprotein 25L2
p24 family protein alpha-2
p24alpha2
transmembrane emp24 protein transport domain containing 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026211.3NP_080487.2  transmembrane emp24 domain-containing protein 9 precursor

    See identical proteins and their annotated locations for NP_080487.2

    Status: VALIDATED

    Source sequence(s)
    AK010259, BY334399, CF382327
    Consensus CDS
    CCDS49277.1
    UniProtKB/Swiss-Prot
    Q99KF1, Q9CX02
    UniProtKB/TrEMBL
    Q3U7N8, Q6PDC2
    Related
    ENSMUSP00000105531.4, ENSMUST00000109905.5
    Conserved Domains (1) summary
    pfam01105
    Location:37230
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    55740948..55745510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)