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Fam171a1 family with sequence similarity 171, member A1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 680259, updated on 27-Nov-2024

Summary

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Symbol
Fam171a1provided by RGD
Full Name
family with sequence similarity 171, member A1provided by RGD
Primary source
RGD:1594172
See related
EnsemblRapid:ENSRNOG00000016534 AllianceGenome:RGD:1594172
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in regulation of cell shape and stress fiber assembly. Predicted to be located in plasma membrane. Orthologous to human FAM171A1 (family with sequence similarity 171 member A1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 17297.1), Thymus (RPKM 17232.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam171a1 in Genome Data Viewer
Location:
17q12.3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (79933742..80057495, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (75024582..75148348, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (79030150..79149480, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene ribonuclease P/MRP subunit p38 Neighboring gene N-myristoyltransferase 2 Neighboring gene uncharacterized LOC134482749 Neighboring gene uncharacterized LOC134482750 Neighboring gene integrin subunit alpha 8 Neighboring gene uncharacterized LOC120097958 Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Astroprincin (FAM171A1, C10orf38): A Regulator of Human Cell Shape and Invasive Growth. Rasila T, et al. Am J Pathol, 2019 Jan. PMID 30312582
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in regulation of cell shape IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of cell shape ISO
Inferred from Sequence Orthology
more info
  
involved_in stress fiber assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in stress fiber assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein FAM171A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432313.1 → NP_001419242.1  protein FAM171A1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0A8I6AEW7

  2. NM_001432314.1 → NP_001419243.1  protein FAM171A1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    79933742..80057495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096412.1 → XP_038952340.1  protein FAM171A1 isoform X3

    UniProtKB/TrEMBL
    A6JM27
    Conserved Domains (1) summary
    pfam10577
    Location:1 → 766
    UPF0560; Uncharacterized protein family UPF0560

  2. XM_039096410.1 → XP_038952338.1  protein FAM171A1 isoform X1

    UniProtKB/TrEMBL
    D4A7Y4
    Related
    ENSRNOP00000111460.1, ENSRNOT00000158378.1
    Conserved Domains (1) summary
    pfam10577
    Location:52 → 909
    UPF0560; Uncharacterized protein family UPF0560

  3. XM_039096411.1 → XP_038952339.1  protein FAM171A1 isoform X2

    Related
    ENSRNOP00000091660.1, ENSRNOT00000106690.2
    Conserved Domains (1) summary
    pfam10577
    Location:34 → 891
    UPF0560; Uncharacterized protein family UPF0560

  4. XM_039096413.2 → XP_038952341.1  protein FAM171A1 isoform X3

    Conserved Domains (1) summary
    pfam10577
    Location:1 → 766
    UPF0560; Uncharacterized protein family UPF0560
Nucleotide Protein Strain
Heading Accession and Version

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