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Maip1 matrix AAA peptidase interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 68115, updated on 27-Nov-2024

Summary

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Official Symbol
Maip1provided by MGI
Official Full Name
matrix AAA peptidase interacting protein 1provided by MGI
Primary source
MGI:MGI:1915365
See related
Ensembl:ENSMUSG00000025971 AllianceGenome:MGI:1915365
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9430016H08Rik
Summary
Predicted to enable ribosome binding activity. Predicted to be involved in calcium import into the mitochondrion; mitochondrial calcium ion homeostasis; and protein insertion into mitochondrial inner membrane from matrix. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrial inner membrane. Orthologous to human MAIP1 (matrix AAA peptidase interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 13.0), placenta adult (RPKM 10.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Maip1 in Genome Data Viewer
Location:
1 C1.3; 1 28.79 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (57445425..57457112)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (57406266..57417953)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930558J18 gene Neighboring gene RIKEN cDNA 1700066M21 gene Neighboring gene STARR-seq mESC enhancer starr_00984 Neighboring gene tRNA-yW synthesizing protein 5 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:57463249-57463358 Neighboring gene predicted gene, 22371 Neighboring gene predicted gene, 53555 Neighboring gene STARR-seq mESC enhancer starr_00987

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Chai G, et al. Neuron, 2021 Jan 20. PMID 33220177, Free PMC Article
  2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in calcium import into the mitochondrion ISO
Inferred from Sequence Orthology
more info
  
involved_in calcium import into the mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mitochondrial calcium ion homeostasis ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrial calcium ion homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein insertion into mitochondrial inner membrane from matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein insertion into mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in protein insertion into mitochondrial membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
m-AAA protease-interacting protein 1, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081181.3 → NP_001074650.1  m-AAA protease-interacting protein 1, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001074650.1

    Status: VALIDATED

    Source sequence(s)
    AC161493, AK079116
    Consensus CDS
    CCDS48266.1
    UniProtKB/Swiss-Prot
    Q8BHE8, Q8R3N9
    Related
    ENSMUSP00000027114.6, ENSMUST00000027114.6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    57445425..57457112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_026564.1: Suppressed sequence

    Description
    NM_026564.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BHE8.1 GenPept UniProtKB/Swiss-Prot:Q8BHE8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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