Rps27l ribosomal protein S27-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rps27lprovided by RGD
Official Full Name: ribosomal protein S27-likeprovided by RGD
Primary source: RGD:1595396
See related: EnsemblRapid:ENSRNOG00000050473 AllianceGenome:RGD:1595396
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Rps27l1
Summary: Predicted to enable RNA binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and translation activator activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in intracellular signal transduction; positive regulation of protein metabolic process; and ribosomal small subunit assembly. Predicted to be located in nucleus. Predicted to be part of cytosolic small ribosomal subunit. Orthologous to human RPS27L (ribosomal protein S27 like). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Liver (RPKM 498.5), Muscle (RPKM 424.9) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 8q24

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (76443658..76448593)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (67562483..67567418)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (72741155..72746090)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables cysteine-type endopeptidase activator activity involved in apoptotic process	IEA Inferred from Electronic Annotation more info
enables cysteine-type endopeptidase activator activity involved in apoptotic process	ISO Inferred from Sequence Orthology more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
enables translation activator activity	IEA Inferred from Electronic Annotation more info
enables translation activator activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	IEA Inferred from Electronic Annotation more info
involved_in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IEA Inferred from Electronic Annotation more info
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	ISO Inferred from Sequence Orthology more info
involved_in mitotic G1 DNA damage checkpoint signaling	IEA Inferred from Electronic Annotation more info
involved_in mitotic G1 DNA damage checkpoint signaling	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cysteine-type endopeptidase activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of translation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of translation	ISO Inferred from Sequence Orthology more info
involved_in ribosomal small subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
part_of cytosolic small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: small ribosomal subunit protein eS27-like

Names: 40S ribosomal protein S27-like; ribosomal protein S27; ribosomal protein S27-like 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001276477.1 → NP_001263406.1 small ribosomal subunit protein eS27-like

See identical proteins and their annotated locations for NP_001263406.1

Status: VALIDATED

Source sequence(s)

CB712651, JAXUCZ010000008

UniProtKB/Swiss-Prot

P24051

UniProtKB/TrEMBL

A0A8L2QXZ3, A6KEZ8

Related

ENSRNOP00000071243.1, ENSRNOT00000090977.3

Conserved Domains (1) summary

PLN00209
Location:6 → 82

PLN00209; ribosomal protein S27; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

76443658..76448593

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039082149.2 → XP_038938077.1 small ribosomal subunit protein eS27-like isoform X2

UniProtKB/Swiss-Prot

P24051

UniProtKB/TrEMBL

A0A8L2QXZ3, A6KEZ8

Conserved Domains (1) summary

PLN00209
Location:6 → 82

PLN00209; ribosomal protein S27; Provisional
XM_063266130.1 → XP_063122200.1 small ribosomal subunit protein eS27-like isoform X1

UniProtKB/TrEMBL

A0A8L2QXZ3
XM_063266131.1 → XP_063122201.1 small ribosomal subunit protein eS27-like isoform X3

UniProtKB/TrEMBL

A0A8I6AWD8, A6J6K5