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Ism2 isthmin 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 681936, updated on 27-Nov-2024

Summary

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Official Symbol
Ism2provided by RGD
Official Full Name
isthmin 2provided by RGD
Primary source
RGD:1589343
See related
EnsemblRapid:ENSRNOG00000050312 AllianceGenome:RGD:1589343
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human ISM2 (isthmin 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 23.3), Brain (RPKM 7.7) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ism2 in Genome Data Viewer
Location:
6q31
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (112652772..112675098, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (106921213..106944291, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (111309054..111329967, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479236 Neighboring gene VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog Neighboring gene activator of Hsp90 ATPase activity 1 Neighboring gene uncharacterized LOC134479239 Neighboring gene serine palmitoyltransferase, long chain base subunit 2 Neighboring gene uncharacterized LOC134479238 Neighboring gene uncharacterized LOC120103582

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
isthmin 2; isthmin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432128.1 → NP_001419057.1  isthmin 2 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    M0RD17

  2. NM_001432129.1 → NP_001419058.1  isthmin 2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  3. NM_001432132.1 → NP_001419061.1  isthmin 2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6A9X1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    112652772..112675098 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262685.1 → XP_063118755.1  isthmin-2 isoform X3

  2. XM_063262684.1 → XP_063118754.1  isthmin-2 isoform X2

  3. XM_008764895.4 → XP_008763117.1  isthmin-2 isoform X1

    Related
    ENSRNOP00000090028.2, ENSRNOT00000106430.2
    Conserved Domains (1) summary
    cl02758
    Location:316 → 476
    AMOP; AMOP domain

RNA

  1. XR_010052295.1 RNA Sequence

  2. XR_010052293.1 RNA Sequence

  3. XR_005506125.2 RNA Sequence

  4. XR_010052294.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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