Sumo4 small ubiquitin-like modifier 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Sumo4provided by RGD
Full Name: small ubiquitin-like modifier 4provided by RGD
Primary source: RGD:1595256
See related: EnsemblRapid:ENSRNOG00000063545 AllianceGenome:RGD:1595256
Gene type: pseudo
RefSeq status: INFERRED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Sumo2l
Summary: Predicted to enable protein tag activity and ubiquitin-like protein ligase binding activity. Predicted to be involved in protein sumoylation. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus 5. Orthologous to human SUMO4 (small ubiquitin like modifier 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 5q12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (19896946..19897930)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (15099320..15100304)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (14983382..14984134)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SUMO4 plays a role in regulating NF-kappaB signaling in glomerular cells from diabetic rats
Title: Inflammatory factor-specific sumoylation regulates NF-κB signalling in glomerular cells from diabetic rats.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Other Names

SMT3 suppressor of mif two 3 homolog 2-like
small ubiquitin-related modifier 2

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein tag activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-like protein ligase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein sumoylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.