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Cyp2d13 cytochrome P450, family 2, subfamily d, polypeptide 13 [ Mus musculus (house mouse) ]

Gene ID: 68444, updated on 27-Nov-2024

Summary

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Official Symbol
Cyp2d13provided by MGI
Official Full Name
cytochrome P450, family 2, subfamily d, polypeptide 13provided by MGI
Primary source
MGI:MGI:88605
See related
Ensembl:ENSMUSG00000118516 AllianceGenome:MGI:88605
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1300007K12Rik
Summary
This gene is one of numerous cytochrome P450 genes that are present in several clusters throughout the genome, and it is a member of the family 2, subfamily d group of genes. This gene does not contain a functional open reading fame, and it is thus classified as a transcribed pseudogene. However, transcripts with a 1 nt deletion relative to the reference genome sequence have been found in some strains, and these would potentially encode a cytochrome P450 polypeptide. [provided by RefSeq, Apr 2024]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Expression
Restricted expression toward liver adult (RPKM 173.2) See more
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Genomic context

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See Cyp2d13 in Genome Data Viewer
Location:
15 E1; 15 38.67 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (82520951..82526246, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (82636750..82642045, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily d, polypeptide 34, pseudogene Neighboring gene cytochrome P450, family 2, subfamily d, polypeptide 34 Neighboring gene cytochrome P450, family 2, subfamily d, member 35, pseudogene Neighboring gene cytochrome P450, family 2, subfamily d, polypeptide 36, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Nelson DR, et al. Pharmacogenetics, 2004 Jan. PMID 15128046
  2. Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Kamileri I, et al. Proc Natl Acad Sci U S A, 2012 Feb 21. PMID 22323595, Free PMC Article
  3. The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. Nelson DR, et al. DNA Cell Biol, 1993 Jan-Feb. PMID 7678494
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

General protein information

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Preferred Names
cytochrome P450, family 2, subfamily d, polypeptide 13
Names
cytochrome P450, 2d13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429617.2 → NP_001416546.1  cytochrome P450, family 2, subfamily d, polypeptide 13

    Status: VALIDATED

    Source sequence(s)
    AC118710, BC018344

RNA

  1. NR_190749.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC118710

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    82520951..82526246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003552.1: Suppressed sequence

    Description
    NR_003552.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version

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