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Gng13 G protein subunit gamma 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685451, updated on 27-Nov-2024

Summary

Official Symbol
Gng13provided by RGD
Official Full Name
G protein subunit gamma 13provided by RGD
Primary source
RGD:1593806
See related
EnsemblRapid:ENSRNOG00000039350 AllianceGenome:RGD:1593806
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hg3j
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway and sensory perception of taste. Predicted to be located in dendrite. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in synapse. Orthologous to human GNG13 (G protein subunit gamma 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 145.9), Kidney (RPKM 74.8) and 2 other tissues See more
Orthologs
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Genomic context

See Gng13 in Genome Data Viewer
Location:
10q12
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15245698..15247602)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14741179..14743083)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15088935..15090839)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene lipase maturation factor 1 Neighboring gene uncharacterized LOC120095315 Neighboring gene chromosome transmission fidelity factor 18 Neighboring gene RNA pseudouridine synthase domain containing 1 Neighboring gene mesothelin-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
Names
guanine nucleotide binding protein (G protein), gamma 13
heterotrimeric guanine nucleotide-binding protein 3j

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135918.1NP_001129390.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13

    See identical proteins and their annotated locations for NP_001129390.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HD38
    Related
    ENSRNOP00000030270.6, ENSRNOT00000030273.6
    Conserved Domains (1) summary
    cd00068
    Location:661
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15245698..15247602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246034.5XP_006246096.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 isoform X1

    See identical proteins and their annotated locations for XP_006246096.1

    UniProtKB/TrEMBL
    A6HD38
    Conserved Domains (1) summary
    cd00068
    Location:661
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors