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Ccdc57 coiled-coil domain containing 57 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688324, updated on 14-Nov-2024

Summary

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Symbol
Ccdc57provided by RGD
Full Name
coiled-coil domain containing 57provided by RGD
Primary source
RGD:1590047
See related
EnsemblRapid:ENSRNOG00000047531 AllianceGenome:RGD:1590047
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in several processes, including G2/M transition of mitotic cell cycle; cilium assembly; and microtubule cytoskeleton organization. Predicted to be located in centriolar satellite; centriole; and spindle microtubule. Orthologous to human CCDC57 (coiled-coil domain containing 57). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 47.6), Kidney (RPKM 30.7) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccdc57 in Genome Data Viewer
Location:
10q32.3
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (106591106..106694740, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (106092784..106196405, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (110046012..110110775, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095225 Neighboring gene fatty acid synthase Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3, regulatory, pseudogene 2 Neighboring gene solute carrier family 16 member 3 Neighboring gene casein kinase 1, delta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in G2/M transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in centriole replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in centriole replication ISO
Inferred from Sequence Orthology
more info
  
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule nucleation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in centriolar satellite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in spindle microtubule ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain containing 57; coiled-coil domain-containing protein 57

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    106591106..106694740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270205.1 → XP_063126275.1  coiled-coil domain-containing protein 57 isoform X2

  2. XM_063270202.1 → XP_063126272.1  coiled-coil domain-containing protein 57 isoform X1

  3. XM_063270204.1 → XP_063126274.1  coiled-coil domain-containing protein 57 isoform X2

  4. XM_039087556.2 → XP_038943484.1  coiled-coil domain-containing protein 57 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZSM9
    Conserved Domains (3) summary
    PHA03307
    Location:911 → 1135
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:28 → 718
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53 → 394
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  5. XM_039087567.2 → XP_038943495.1  coiled-coil domain-containing protein 57 isoform X9

    UniProtKB/TrEMBL
    A0A8I5ZSM9
    Conserved Domains (3) summary
    PHA03307
    Location:778 → 1002
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:126 → 409
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:195 → 584
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  6. XM_039087568.2 → XP_038943496.1  coiled-coil domain-containing protein 57 isoform X9

    UniProtKB/TrEMBL
    A0A8I5ZSM9
    Conserved Domains (3) summary
    PHA03307
    Location:778 → 1002
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:126 → 409
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:195 → 584
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  7. XM_039087565.2 → XP_038943493.1  coiled-coil domain-containing protein 57 isoform X7

    UniProtKB/TrEMBL
    A0A8I5ZSM9
    Conserved Domains (2) summary
    PHA03307
    Location:816 → 1040
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:28 → 623
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  8. XM_039087563.2 → XP_038943491.1  coiled-coil domain-containing protein 57 isoform X6

    UniProtKB/TrEMBL
    M0R9E4
    Conserved Domains (2) summary
    PHA03307
    Location:841 → 1065
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:36 → 744
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  9. XM_039087559.2 → XP_038943487.1  coiled-coil domain-containing protein 57 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZSM9
    Conserved Domains (3) summary
    PHA03307
    Location:883 → 1107
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:321 → 690
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53 → 394
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  10. XM_063270211.1 → XP_063126281.1  coiled-coil domain-containing protein 57 isoform X10

  11. XM_063270209.1 → XP_063126279.1  coiled-coil domain-containing protein 57 isoform X10

  12. XM_063270210.1 → XP_063126280.1  coiled-coil domain-containing protein 57 isoform X10

  13. XM_063270208.1 → XP_063126278.1  coiled-coil domain-containing protein 57 isoform X10

  14. XM_063270206.1 → XP_063126276.1  coiled-coil domain-containing protein 57 isoform X10

  15. XM_063270207.1 → XP_063126277.1  coiled-coil domain-containing protein 57 isoform X10

  16. XM_039087569.2 → XP_038943497.1  coiled-coil domain-containing protein 57 isoform X11

    UniProtKB/TrEMBL
    M0R9E4
    Conserved Domains (3) summary
    PHA03307
    Location:649 → 873
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:1 → 280
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:66 → 455
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  17. XM_039087566.2 → XP_038943494.1  coiled-coil domain-containing protein 57 isoform X8

    UniProtKB/TrEMBL
    M0R9E4
    Related
    ENSRNOP00000066112.4, ENSRNOT00000071893.4
    Conserved Domains (2) summary
    PHA03307
    Location:813 → 1037
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:28 → 620
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  18. XM_039087571.2 → XP_038943499.1  coiled-coil domain-containing protein 57 isoform X12

    Conserved Domains (2) summary
    PHA03307
    Location:566 → 790
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:3 → 373
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  19. XM_063270203.1 → XP_063126273.1  coiled-coil domain-containing protein 57 isoform X2

    Related
    ENSRNOP00000091858.2, ENSRNOT00000098223.2

  20. XM_039087570.1 → XP_038943498.1  coiled-coil domain-containing protein 57 isoform X11

    UniProtKB/TrEMBL
    M0R9E4
    Conserved Domains (3) summary
    PHA03307
    Location:649 → 873
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:1 → 280
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:66 → 455
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  21. XM_039087561.2 → XP_038943489.1  coiled-coil domain-containing protein 57 isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZSM9
    Conserved Domains (2) summary
    COG1196
    Location:28 → 718
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53 → 394
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  22. XM_039087562.2 → XP_038943490.1  coiled-coil domain-containing protein 57 isoform X5

    UniProtKB/TrEMBL
    A0A8I5Y209
    Conserved Domains (2) summary
    COG1196
    Location:28 → 718
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53 → 394
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  23. XM_039087572.2 → XP_038943500.1  coiled-coil domain-containing protein 57 isoform X13

    Conserved Domains (1) summary
    TIGR02168
    Location:53 → 394
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RNA

  1. XR_010055923.1 RNA Sequence

  2. XR_005490602.2 RNA Sequence

  3. XR_005490603.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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