U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mettl27 methyltransferase like 27 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688407, updated on 4-Jan-2025

Summary

Official Symbol
Mettl27provided by RGD
Official Full Name
methyltransferase like 27provided by RGD
Primary source
RGD:1588881
See related
EnsemblRapid:ENSRNOG00000046700 AllianceGenome:RGD:1588881
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Wbscr27
Summary
Orthologous to human METTL27 (methyltransferase like 27). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 74.5), Heart (RPKM 50.2) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Mettl27 in Genome Data Viewer
Location:
12q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (27394067..27403220, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (21757545..21766698, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (24767351..24775891, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene actin related protein 2/3 complex, subunit 5-like, pseudogene 3 Neighboring gene claudin 4 Neighboring gene claudin-4-like Neighboring gene uncharacterized LOC120095920 Neighboring gene transmembrane protein 270

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
methyltransferase-like protein 27
Names
Williams Beuren syndrome chromosome region 27
Williams-Beuren syndrome chromosomal region 27 protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109499.3NP_001102969.1  methyltransferase-like protein 27

    See identical proteins and their annotated locations for NP_001102969.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A0A8I6AP98, A6J0G7, D4AED6
    Conserved Domains (1) summary
    pfam13649
    Location:71162
    Methyltransf_25; Methyltransferase domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    27394067..27403220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089764.1XP_038945692.1  methyltransferase-like protein 27 isoform X2

    UniProtKB/TrEMBL
    D4AED6
    Conserved Domains (2) summary
    COG4976
    Location:30115
    COG4976; Predicted methyltransferase, contains TPR repeat [General function prediction only]
    pfam13649
    Location:71109
    Methyltransf_25; Methyltransferase domain
  2. XM_039089763.1XP_038945691.1  methyltransferase-like protein 27 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZPD6, D4AED6
    Related
    ENSRNOP00000065369.3, ENSRNOT00000074851.3
    Conserved Domains (1) summary
    pfam13649
    Location:71162
    Methyltransf_25; Methyltransferase domain