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Rnf208 ring finger protein 208 [ Mus musculus (house mouse) ]

Gene ID: 68846, updated on 4-Jan-2025

Summary

Official Symbol
Rnf208provided by MGI
Official Full Name
ring finger protein 208provided by MGI
Primary source
MGI:MGI:1916096
See related
Ensembl:ENSMUSG00000044628 AllianceGenome:MGI:1916096
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110061N23Rik
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination. Predicted to be located in cytosol and nucleoplasm. Is expressed in nervous system and neural retina. Orthologous to human RNF208 (ring finger protein 208). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Rnf208 in Genome Data Viewer
Location:
2 A3; 2 17.1 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25132941..25134273)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25242929..25244261)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ring finger protein 224 Neighboring gene cysteine rich tail 1 Neighboring gene NADPH dependent diflavin oxidoreductase 1 Neighboring gene transmembrane protein 203 Neighboring gene STARR-positive B cell enhancer ABC_E805 Neighboring gene taperin

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in protein autoubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in protein autoubiquitination ISO
Inferred from Sequence Orthology
more info
 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176834.2NP_789804.2  RING finger protein 208

    See identical proteins and their annotated locations for NP_789804.2

    Status: VALIDATED

    Source sequence(s)
    AK004344, BQ031423, CX206020
    Consensus CDS
    CCDS15757.2
    UniProtKB/Swiss-Prot
    A2AI04, B2FDG8, Q8BTC4, Q8K0W3
    Related
    ENSMUSP00000109995.2, ENSMUST00000114355.2
    Conserved Domains (1) summary
    cd16559
    Location:144197
    RING-HC_RNF208; RING finger, HC subclass, found in RING finger protein 208 (RNF208) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    25132941..25134273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)