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Wdr36 WD repeat domain 36 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688637, updated on 27-Nov-2024

Summary

Official Symbol
Wdr36provided by RGD
Official Full Name
WD repeat domain 36provided by RGD
Primary source
RGD:1586463
See related
EnsemblRapid:ENSRNOG00000027355 AllianceGenome:RGD:1586463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to act upstream of or within regulation of axon extension and retina homeostasis. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in glaucoma and primary open angle glaucoma. Orthologous to human WDR36 (WD repeat domain 36). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 143.6), Spleen (RPKM 127.6) and 9 other tissues See more
Orthologs
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Genomic context

See Wdr36 in Genome Data Viewer
Location:
18p12
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (24747812..24783704)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (24473657..24501773)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (25637475..25665801)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) 30 Neighboring gene thymic stromal lymphopoietin Neighboring gene uncharacterized LOC134482926 Neighboring gene calcium/calmodulin-dependent protein kinase IV Neighboring gene uncharacterized LOC120098266

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of axon extension ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within retina homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of Pwp2p-containing subcomplex of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
WD repeat-containing protein 36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001400815.1NP_001387744.1  WD repeat-containing protein 36

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    Related
    ENSRNOP00000036935.7, ENSRNOT00000031530.9

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    24747812..24783704
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277596.1XP_063133666.1  WD repeat-containing protein 36 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A876
    Related
    ENSRNOP00000066707.3, ENSRNOT00000075283.3

RNA

  1. XR_010059604.1 RNA Sequence

  2. XR_010059605.1 RNA Sequence