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Tmem120b transmembrane protein 120B [ Rattus norvegicus (Norway rat) ]

Gene ID: 690137, updated on 27-Nov-2024

Summary

Official Symbol
Tmem120bprovided by RGD
Official Full Name
transmembrane protein 120Bprovided by RGD
Primary source
RGD:1584031
See related
EnsemblRapid:ENSRNOG00000048050 AllianceGenome:RGD:1584031
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in fat cell differentiation and protein heterooligomerization. Predicted to be active in nuclear inner membrane. Orthologous to human TMEM120B (transmembrane protein 120B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 46.0), Thymus (RPKM 35.0) and 9 other tissues See more
Orthologs
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Genomic context

See Tmem120b in Genome Data Viewer
Location:
12q16
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (39108280..39148090, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (33447441..33487257, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (38894847..38916237, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene SET domain containing 1B, histone lysine methyltransferase Neighboring gene ras homolog family member F, filopodia associated Neighboring gene ribosomal protein L32, pseudogene 9 Neighboring gene MORN repeat containing 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
NOT enables monoatomic ion channel activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in fat cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein heterooligomerization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in nuclear inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear inner membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271309.2NP_001258238.1  transmembrane protein 120B

    See identical proteins and their annotated locations for NP_001258238.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A0A8I5ZLE9, A6J168, M0R6Y6
    Related
    ENSRNOP00000065199.2, ENSRNOT00000074517.5
    Conserved Domains (1) summary
    pfam07851
    Location:9332
    TMPIT; TMPIT-like protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    39108280..39148090 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005491673.1 RNA Sequence