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Pdf peptide deformylase (mitochondrial) [ Rattus norvegicus (Norway rat) ]

Gene ID: 690214, updated on 27-Nov-2024

Summary

Official Symbol
Pdfprovided by RGD
Official Full Name
peptide deformylase (mitochondrial)provided by RGD
Primary source
RGD:1582894
See related
EnsemblRapid:ENSRNOG00000022303 AllianceGenome:RGD:1582894
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable peptide deformylase activity. Predicted to be involved in several processes, including N-terminal protein amino acid modification; co-translational protein modification; and peptidyl-methionine modification. Predicted to be active in mitochondrion. Orthologous to human PDF (peptide deformylase, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 123.4), Kidney (RPKM 108.1) and 9 other tissues See more
Orthologs
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Genomic context

See Pdf in Genome Data Viewer
Location:
19q12
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (51859159..51861281, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (34949408..34951621, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (39244242..39246636, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene syntrophin, beta 2 Neighboring gene U6 spliceosomal RNA Neighboring gene vacuolar protein sorting 4 homolog A Neighboring gene uncharacterized LOC134483350 Neighboring gene component of oligomeric golgi complex 8 Neighboring gene nucleolar pre-rRNA processing protein NIP7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables peptide deformylase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables peptide deformylase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in N-terminal protein amino acid modification ISO
Inferred from Sequence Orthology
more info
 
involved_in co-translational protein modification IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in peptidyl-methionine modification ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
peptide deformylase, mitochondrial
Names
peptide deformylase-like protein-like
NP_001388000.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401071.1NP_001388000.1  peptide deformylase, mitochondrial precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    F1LVY9
    Related
    ENSRNOP00000036742.5, ENSRNOT00000036634.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    51859159..51861281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)