Tafa3 TAFA chemokine like family member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tafa3provided by RGD
Official Full Name: TAFA chemokine like family member 3provided by RGD
Primary source: RGD:1587462
See related: EnsemblRapid:ENSRNOG00000030253 AllianceGenome:RGD:1587462
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam19a3
Summary: Predicted to enable receptor ligand activity. Predicted to be involved in negative regulation of microglial cell activation and positive regulation of microglial cell activation. Predicted to be active in extracellular space. Orthologous to human TAFA3 (TAFA chemokine like family member 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Spleen (RPKM 37.0), Lung (RPKM 25.3) and 9 other tissues See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (194952499..194968776, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (192264153..192280356, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (207249000..207258962, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables receptor ligand activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of microglial cell activation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of microglial cell activation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of microglial cell activation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of microglial cell activation	ISO Inferred from Sequence Orthology more info
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info

Names: family with sequence similarity 19 (chemokine (C-C motif)-like), member A3; family with sequence similarity 19 member A3, C-C motif chemokine like