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Elof1 elongation factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691193, updated on 27-Nov-2024

Summary

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Official Symbol
Elof1provided by RGD
Official Full Name
elongation factor 1provided by RGD
Primary source
RGD:1587399
See related
EnsemblRapid:ENSRNOG00000014284 AllianceGenome:RGD:1587399
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309855
Summary
Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Predicted to be part of transcription elongation factor complex. Orthologous to human ELOF1 (elongation factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 479.1), Kidney (RPKM 141.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Elof1 in Genome Data Viewer
Location:
8q13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (28921338..28926612, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (20645336..20650888, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (23125987..23130980, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094091 Neighboring gene ECSIT signaling integrator Neighboring gene calponin 1 Neighboring gene acid phosphatase 5, tartrate resistant Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class Y like 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class Y

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA polymerase II complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transcription elongation factor 1 homolog
Names
ELF1 homolog, elongation factor 1
elongation factor 1 homolog (ELF1, S. cerevisiae)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126098.1 → NP_001119570.1  transcription elongation factor 1 homolog

    See identical proteins and their annotated locations for NP_001119570.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473993
    UniProtKB/TrEMBL
    A6JNZ0, D4AEE9
    Related
    ENSRNOP00000019140.4, ENSRNOT00000019140.7
    Conserved Domains (1) summary
    pfam05129
    Location:20 → 80
    Elf1; Transcription elongation factor Elf1 like

  2. NM_001429182.1 → NP_001416111.1  transcription elongation factor 1 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A6JNZ0, D4AEE9

  3. NM_001429183.1 → NP_001416112.1  transcription elongation factor 1 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A6JNZ0, D4AEE9

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    28921338..28926612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039082187.2 → XP_038938115.2  transcription elongation factor 1 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8I6AF92

  2. XM_063266180.1 → XP_063122250.1  transcription elongation factor 1 homolog isoform X1

  3. XM_008765987.4 → XP_008764209.1  transcription elongation factor 1 homolog isoform X5

    Conserved Domains (1) summary
    pfam05129
    Location:20 → 80
    Elf1; Transcription elongation factor Elf1 like

  4. XM_063266181.1 → XP_063122251.1  transcription elongation factor 1 homolog isoform X4

  5. XM_039082188.2 → XP_038938116.2  transcription elongation factor 1 homolog isoform X3

    UniProtKB/TrEMBL
    A0A8I6AI25
Nucleotide Protein Strain
Heading Accession and Version

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