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H4c8 H4 clustered histone 8 [ Mus musculus (house mouse) ]

Gene ID: 69386, updated on 27-Nov-2024

Summary

Official Symbol
H4c8provided by MGI
Official Full Name
H4 clustered histone 8provided by MGI
Primary source
MGI:MGI:2448427
See related
Ensembl:ENSMUSG00000060981 AllianceGenome:MGI:2448427
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2c8; H4c1; H4c2; H4c3; H4c4; H4c6; H4c9; H4c11; H4c12; H4c14; H4c16; H4f16; Hist1h4h; 1700024H08Rik
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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Genomic context

See H4c8 in Genome Data Viewer
Location:
13 A3.1; 13 9.77 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23715214..23715648)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23531044..23531478)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5381 Neighboring gene nuclear encoded tRNA arginine 1 (anticodon TCG) Neighboring gene predicted gene 11335 Neighboring gene nuclear encoded tRNA methionine 9 (anticodon CAT) Neighboring gene STARR-positive B cell enhancer ABC_E4057 Neighboring gene H2A clustered histone 10 Neighboring gene STARR-positive B cell enhancer mm9_chr13:23627005-23627306 Neighboring gene H3 clustered histone 8

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC41466

Gene Ontology Provided by MGI

Component Evidence Code Pubs
part_of CENP-A containing nucleosome ISO
Inferred from Sequence Orthology
more info
 
part_of nucleosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H4
Names
H4 histone family, member A
histone 1, H4h
histone cluster 1, H4h

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153173.4NP_694813.1  histone H4

    See identical proteins and their annotated locations for NP_694813.1

    Status: REVIEWED

    Source sequence(s)
    AL592149
    Consensus CDS
    CCDS26340.1
    UniProtKB/Swiss-Prot
    A0AUM5, A4FUP8, A4QMY0, P62806, Q0VDL9, Q2M2Q5, Q5T006, Q6PDS7, Q811M0, Q9D0C9, Q9D6Q8
    UniProtKB/TrEMBL
    B2RTM0
    Related
    ENSMUSP00000100037.4, ENSMUST00000102972.6
    Conserved Domains (1) summary
    PLN00035
    Location:1103
    PLN00035; histone H4; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    23715214..23715648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)