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Ubl7 ubiquitin-like 7 (bone marrow stromal cell-derived) [ Mus musculus (house mouse) ]

Gene ID: 69459, updated on 27-Nov-2024

Summary

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Official Symbol
Ubl7provided by MGI
Official Full Name
ubiquitin-like 7 (bone marrow stromal cell-derived)provided by MGI
Primary source
MGI:MGI:1916709
See related
Ensembl:ENSMUSG00000055720 AllianceGenome:MGI:1916709
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2300004C15Rik
Summary
Predicted to enable molecular adaptor activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol. Orthologous to human UBL7 (ubiquitin like 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 213.4), adrenal adult (RPKM 70.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Ubl7 in Genome Data Viewer
Location:
9 B; 9 31.63 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57818280..57837624)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57910978..57929970)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_24248 Neighboring gene STARR-seq mESC enhancer starr_24249 Neighboring gene predicted gene 7547 Neighboring gene meiotic nuclear divisions 1 homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_24251 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:57758633-57758820 Neighboring gene sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:57804760-57804959 Neighboring gene STARR-positive B cell enhancer ABC_E8291 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:57816329-57816438 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:57819923-57820197 Neighboring gene STARR-seq mESC enhancer starr_24252 Neighboring gene STARR-positive B cell enhancer ABC_E2890 Neighboring gene STARR-seq mESC enhancer starr_24253 Neighboring gene cytochrome P450, family 11, subfamily a, polypeptide 1 Neighboring gene ADP-ribosylation factor-like 6 interacting protein 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic Dissection of a QTL Affecting Bone Geometry. Sabik OL, et al. G3 (Bethesda), 2017 Mar 10. PMID 28082324, Free PMC Article
  2. UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS. Jiang W, et al. Cell Rep, 2023 Mar 28. PMID 36943869
  3. An Interaction Landscape of Ubiquitin Signaling. Zhang X, et al. Mol Cell, 2017 Mar 2. PMID 28190767
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular adaptor activity ISO
Inferred from Sequence Orthology
more info
  
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquitin-like protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122873.2 → NP_001116345.1  ubiquitin-like protein 7 isoform 1

    See identical proteins and their annotated locations for NP_001116345.1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    Consensus CDS
    CCDS23234.1
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5
    Related
    ENSMUSP00000126019.2, ENSMUST00000163329.2
    Conserved Domains (2) summary
    cd14326
    Location:346 → 375
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
    cd01815
    Location:7 → 98
    Ubl_UBL7; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 7 (UBL7) and similar proteins

  2. NM_001413501.1 → NP_001400430.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5
    Related
    ENSMUSP00000149748.2, ENSMUST00000216841.2

  3. NM_001413502.1 → NP_001400431.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  4. NM_001413503.1 → NP_001400432.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  5. NM_001413504.1 → NP_001400433.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  6. NM_001413505.1 → NP_001400434.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  7. NM_001413506.1 → NP_001400435.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  8. NM_001413507.1 → NP_001400436.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  9. NM_001413508.1 → NP_001400437.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  10. NM_001413509.1 → NP_001400438.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  11. NM_001413510.1 → NP_001400439.1  ubiquitin-like protein 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5

  12. NM_001413511.1 → NP_001400440.1  ubiquitin-like protein 7 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC122534

  13. NM_001413512.1 → NP_001400441.1  ubiquitin-like protein 7 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC122534

  14. NM_001413513.1 → NP_001400442.1  ubiquitin-like protein 7 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC122534

  15. NM_001413514.1 → NP_001400443.1  ubiquitin-like protein 7 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246

  16. NM_001413515.1 → NP_001400444.1  ubiquitin-like protein 7 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246

  17. NM_001413516.1 → NP_001400445.1  ubiquitin-like protein 7 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246

  18. NM_001413517.1 → NP_001400446.1  ubiquitin-like protein 7 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246

  19. NM_001413518.1 → NP_001400447.1  ubiquitin-like protein 7 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246

  20. NM_027086.4 → NP_081362.2  ubiquitin-like protein 7 isoform 1

    See identical proteins and their annotated locations for NP_081362.2

    Status: VALIDATED

    Source sequence(s)
    AC122534, AC165246
    Consensus CDS
    CCDS23234.1
    UniProtKB/Swiss-Prot
    E9Q1S0, Q91W67, Q9D7P5
    Related
    ENSMUSP00000150925.2, ENSMUST00000216925.2
    Conserved Domains (2) summary
    cd14326
    Location:346 → 375
    UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
    cd01815
    Location:7 → 98
    Ubl_UBL7; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 7 (UBL7) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    57818280..57837624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91W67.2 GenPept UniProtKB/Swiss-Prot:Q91W67

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