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Rwdd2a RWD domain containing 2A [ Mus musculus (house mouse) ]

Gene ID: 69519, updated on 27-Nov-2024

Summary

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Official Symbol
Rwdd2aprovided by MGI
Official Full Name
RWD domain containing 2Aprovided by MGI
Primary source
MGI:MGI:1916769
See related
Ensembl:ENSMUSG00000032417 AllianceGenome:MGI:1916769
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rwdd2; 1700030C20Rik
Summary
Orthologous to human RWDD2A (RWD domain containing 2A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 18.3), cerebellum adult (RPKM 6.4) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Rwdd2a in Genome Data Viewer
Location:
9 E3.1; 9 46.58 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (86454041..86456952)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (86571988..86574899)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 4 pseudogene Neighboring gene ubiquitin protein ligase E3D Neighboring gene DOP1 leucine zipper like protein A Neighboring gene STARR-positive B cell enhancer ABC_E9332 Neighboring gene phosphoglucomutase 3 Neighboring gene STARR-positive B cell enhancer ABC_E10572 Neighboring gene malic enzyme 1, NADP(+)-dependent, cytosolic Neighboring gene STARR-seq mESC enhancer starr_24835 Neighboring gene RIKEN cDNA A330041J22 gene Neighboring gene predicted gene, 22138

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC144625, MGC144626

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
RWD domain-containing protein 2A
Names
RWD domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145968.1 → NP_001139440.1  RWD domain-containing protein 2A

    See identical proteins and their annotated locations for NP_001139440.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AI848608, BC115692
    Consensus CDS
    CCDS23382.1
    UniProtKB/Swiss-Prot
    Q9D9S3
    UniProtKB/TrEMBL
    Q14BN8
    Related
    ENSMUSP00000137392.2, ENSMUST00000179212.3
    Conserved Domains (2) summary
    pfam05773
    Location:7 → 130
    RWD; RWD domain
    pfam06544
    Location:160 → 281
    DUF1115; Protein of unknown function (DUF1115)

  2. NM_001145969.1 → NP_001139441.1  RWD domain-containing protein 2A

    See identical proteins and their annotated locations for NP_001139441.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AI848608, AK006533, CJ149958, CN836837
    Consensus CDS
    CCDS23382.1
    UniProtKB/Swiss-Prot
    Q9D9S3
    UniProtKB/TrEMBL
    Q14BN8
    Related
    ENSMUSP00000139930.2, ENSMUST00000185566.7
    Conserved Domains (2) summary
    pfam05773
    Location:7 → 130
    RWD; RWD domain
    pfam06544
    Location:160 → 281
    DUF1115; Protein of unknown function (DUF1115)

  3. NM_027100.2 → NP_081376.2  RWD domain-containing protein 2A

    See identical proteins and their annotated locations for NP_081376.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AI848608, BC115691
    Consensus CDS
    CCDS23382.1
    UniProtKB/Swiss-Prot
    Q9D9S3
    UniProtKB/TrEMBL
    Q14BN8
    Related
    ENSMUSP00000034988.4, ENSMUST00000034988.10
    Conserved Domains (2) summary
    pfam05773
    Location:7 → 130
    RWD; RWD domain
    pfam06544
    Location:160 → 281
    DUF1115; Protein of unknown function (DUF1115)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    86454041..86456952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D9S3.1 GenPept UniProtKB/Swiss-Prot:Q9D9S3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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