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fhaB filamentous hemagglutinin/adhesin [ Bordetella pertussis ]

Gene ID: 69601663, updated on 29-Mar-2024

Summary

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Gene symbol
fhaB
Gene description
filamentous hemagglutinin/adhesin
Locus tag
CXD86_RS09095
Gene type
protein coding
RefSeq status
PIPELINE
Organism
Bordetella pertussis (strain: H640, nat-host: Homo sapiens)
Lineage
Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella
Old locus tag
CXD86_09050
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Genomic context

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NZ_CP025371.1Genomic Context describing neighboring genes Neighboring gene virulence factors two-component system sensor histidine kinase BvgS Neighboring gene virulence factors two-component system response regulator BvgA Neighboring gene protein FimA Neighboring gene molecular chaperone FimB

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP025371.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway. Clantin B, et al. Proc Natl Acad Sci U S A, 2004 Apr 20. PMID 15079085, Free PMC Article
  2. Cloning, partial sequence, expression, and antigenic analysis of the filamentous hemagglutinin gene of Bordetella pertussis. Delisse-Gathoye AM, et al. Infect Immun, 1990 Sep. PMID 1696934, Free PMC Article
  3. The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model. Holubova J, et al. PLoS Pathog, 2022 Apr. PMID 35395059, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.
    Title: The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.
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General protein information

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Preferred Names
filamentous hemagglutinin/adhesin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP025371.1 Reference assembly

    Range
    1854427..1865199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010930610.1 filamentous hemagglutinin/adhesin [Bordetella pertussis]

    See identical proteins and their annotated locations for WP_010930610.1

    Status: PIPELINE

    UniProtKB/Swiss-Prot
    P12255, Q45364
    UniProtKB/TrEMBL
    A0A381A265, Q45365, Q8VV99
    Conserved Domains (7) summary
    sd00046
    Location:1440 → 1457
    FHA_bHelix; FHA beta-helical repeat [structural motif]
    NF033176
    Location:290 → 789
    auto_AIDA-I; autotransporter adhesin AIDA-I
    NF033177
    Location:1217 → 1678
    auto_Ag43; autotransporter adhesin Ag43
    pfam05860
    Location:77 → 204
    Haemagg_act; haemagglutination activity domain
    pfam13018
    Location:1 → 23
    ESPR; Extended Signal Peptide of Type V secretion system
    pfam13332
    Location:2919 → 3085
    Fil_haemagg_2; Haemagluttinin repeat
    NF033839
    Location:3218 → 3473
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P12255.4